SCHEMBL458064

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL22745230	0.92	XDH (0.77)	XDHTARBP2ABCC4ABCB11PGR
	SCHEMBL2635992	0.92	XDH (0.83)	XDHTARBP2ABCC4ABCB11PGR
	SCHEMBL31601	0.90	XDH (0.80)	XDHTARBP2ABCC4ABCB11PGR
	SCHEMBL29655618	0.90	XDH (0.80)	XDHTARBP2ABCC4ABCB11PGR
	Febuxostat SCHEMBL29398803	0.89	XDH (1.00)	XDHTARBP2ABCC4ABCB11PGR
	Febuxostat SCHEMBL30161803	0.89	XDH (1.00)	XDHTARBP2ABCC4ABCB11PGR
	Febuxostat SCHEMBL28271887	0.89	XDH (1.00)	XDHTARBP2ABCC4ABCB11PGR
	Febuxostat SCHEMBL249339	0.89	XDH (1.00)	XDHTARBP2ABCC4ABCB11PGR
	SCHEMBL16363788	0.89	XDH (0.85)	XDHTARBP2ABCC4ABCB11PGR
	SCHEMBL301006	0.89	XDH (0.77)	XDHTARBP2ABCC4ABCB11PGR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.