Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NNMT | P40261 | 2/20 | 0.45 |
| ▸ | NPC1 | O15118 | 3/20 | 0.43 |
| ▸ | RAB9A | P51151 | 3/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.43 |
| ▸ | TP53 | P04637 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | RECQL | P46063 | 1/20 | 0.43 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | ACHE | P22303 | 1/20 | 0.41 |
| ▸ | PARP1 | P09874 | 1/20 | 0.41 |
| ▸ | IKBKB | O14920 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12505480 | 0.83 | NNMT (0.50) | NNMTKDM4EMAPK10ALDH1A1ACHE | |
| SCHEMBL29046678 | 0.81 | CYP3A4 (0.53) | NPC1KDM4ERECQLTDP1ALDH1A1 | |
| SCHEMBL25514830 | 0.81 | NNMT (0.45) | NNMTKDM4EMAPK10TDP1ALDH1A1 | |
| SCHEMBL347496 | 0.79 | NNMT (0.46) | NNMTKDM4ESMN1; SMN2MAPK10TDP1 | |
| SCHEMBL9768514 | 0.77 | TDP1 (0.59) | NPC1RAB9ATP53SMN1; SMN2TDP1 | |
| SCHEMBL25514832 | 0.75 | ALDH1A1 (0.54) | NNMTNPC1RAB9AKDM4ESMN1; SMN2 | |
| SCHEMBL14610813 | 0.75 | IKBKB (0.63) | IKBKB | |
| SCHEMBL17779280 | 0.75 | KDM4E (0.47) | NNMTKDM4ETP53SMN1; SMN2TDP1 | |
| SCHEMBL11466514 | 0.74 | GSK3B (0.42) | NNMTNPC1RAB9AKDM4ETP53 | |
| SCHEMBL1863405 | 0.73 | ALDH1A1 (0.49) | NNMTNPC1RAB9AKDM4ESMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080312349-A1 | METHOD OF MAKING AND USING MEMBRANE | GENERAL ELECTRIC COMPANY (US) | 2008-12-18 | — | — | US | disclosed |
| WO-2008103599-A2 | COMPOSITION, ITS USE IN THE PREPARATION OF MEMBRANES, AND SYSTEMS COMPRISING THE MEMBRANES | SABIC INNOVATIVE PLASTICS IP B.V. (NL) | 2008-08-28 | — | — | WO | disclosed |
| US-20080207822-A1 | COMPOSITION AND ASSOCIATED METHOD | GENERAL ELECTRIC COMPANY (US) | 2008-08-28 | — | — | US | disclosed |
| US-20080203012-A1 | MEMBRANE, APPARATUS, AND ASSOCIATED METHOD | GENERAL ELECTRIC COMPANY (US) | 2008-08-28 | — | — | US | disclosed |