Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.49 |
| ▸ | HPGD | P15428 | 4/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.49 |
| ▸ | NNMT | P40261 | 2/20 | 0.44 |
| ▸ | PARP1 | P09874 | 6/20 | 0.43 |
| ▸ | MYC | P01106 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.42 |
| ▸ | JAK1 | P23458 | 1/20 | 0.41 |
| ▸ | TYK2 | P29597 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3395132 | 0.90 | PARP1 (0.47) | ALDH1A1HSD17B10HPGDKDM4ENNMT | |
| SCHEMBL6645354 | 0.84 | NNMT (0.49) | ALDH1A1KDM4ENNMTPARP1LMNA | |
| SCHEMBL9726590 | 0.83 | KDM4E (0.52) | ALDH1A1HSD17B10HPGDKDM4EMYC | |
| SCHEMBL5925554 | 0.83 | KDM4E (0.72) | ALDH1A1HSD17B10HPGDKDM4EPARP1 | |
| SCHEMBL261504 | 0.82 | MAPT (0.56) | ALDH1A1HSD17B10HPGDKDM4ELMNA | |
| SCHEMBL29430315 | 0.82 | ALDH1A1 (0.48) | ALDH1A1HSD17B10HPGDKDM4EPARP1 | |
| SCHEMBL9818242 | 0.82 | ALDH1A1 (0.48) | ALDH1A1HSD17B10HPGDKDM4EPARP1 | |
| SCHEMBL28309500 | 0.82 | L3MBTL1 (0.45) | ALDH1A1HSD17B10HPGDKDM4EPARP1 | |
| SCHEMBL305252 | 0.82 | ALDH1A1 (0.70) | ALDH1A1HSD17B10HPGDKDM4EMYC | |
| SCHEMBL30675634 | 0.82 | ALDH1A1 (0.70) | ALDH1A1HSD17B10HPGDKDM4EMYC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 39 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116855008-A | 80-year-life thermosetting sheath material for cable for nuclear power station and preparation method thereof | 江苏上上电缆集团新材料有限公司 | 2023-10-10 | — | — | CN | claimed |
| WO-2007134421-A1 | 2-VINYL INDOLES, PYRIDO AND AZEPINO INDOLE DERIVATIVES, 2-ALKYNYL INDOLES, 2-ALKYNYL BENZO[b]FURANS, THEIR PRECURSORS AND NOVEL PROCESSES FOR THE PREPARATION THEREOF | LAUTENS MARK (CA) | 2007-11-29 | — | — | WO | claimed |
| EP-4257587-A1 | HYDROXAMATE COMPOUND, PREPARATION METHOD THEREFOR AND APPLICATION THEREOF | Shenzhen Chipscreen Biosciences Co., Ltd. (CN) | 2023-10-11 | — | — | EP | disclosed |
| CN-116855008-A | 80-year-life thermosetting sheath material for cable for nuclear power station and preparation method thereof | 江苏上上电缆集团新材料有限公司 | 2023-10-10 | — | — | CN | disclosed |
| US-20230271975-A1 | IMIDAZOLE-CONTAINING INHIBITORS OF ALK2 KINASE | WILMINGTON TRUST, NATIONAL ASSOCIATION | 2023-08-31 | — | — | US | disclosed |
| US-11661426-B2 | Imidazole-containing inhibitors of ALK2 kinase | BIOCRYST PHARMACEUTICALS, INC. (US) | 2023-05-30 | — | — | US | disclosed |
| WO-2022204363-A1 | GERMINATION/SPROUTING AND FRUIT RIPENING REGULATORS | THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY OF AGRICULTURE (US) | 2022-09-29 | — | — | WO | disclosed |
| WO-2022117016-A1 | HYDROXAMATE COMPOUND, PREPARATION METHOD THEREFOR AND APPLICATION THEREOF | 深圳微芯生物科技股份有限公司 | 2022-06-09 | — | — | WO | disclosed |
| WO-2022100710-A1 | TYROSINE KINASE 2 (TYK2) DEGRADATION COMPOUNDS AND METHODS OF USE | CULLGEN (SHANGHAI) , INC. (CN) | 2022-05-19 | — | — | WO | disclosed |
| EP-3720435-A1 | CRYSTAL FORMS AND PRODUCTION METHODS THEREOF | Sunovion Pharmaceuticals Inc. (US) | 2020-10-14 | — | — | EP | disclosed |
| US-10752624-B2 | Kinase inhibitors | ORIGENIS GMBH (DE) | 2020-08-25 | — | — | US | disclosed |
| US-20050085526-A1 | Indole derivatives useful for the treatment of diseases | BROWN ALAN D (GB) | 2005-04-21 | — | — | US | disclosed |
| EP-1501800-A1 | BOMBESIN ANTAGONISTS | Warner-Lambert Company LLC (US) | 2005-02-02 | — | — | EP | disclosed |
| US-6844362-B2 | Indole derivatives useful for the treatment of diseases | PFIZER INC (US) | 2005-01-18 | — | — | US | disclosed |
| EP-1440966-A1 | Indole derivatives useful for the treatment of diseases | Pfizer Limited (GB) | 2004-07-28 | — | — | EP | disclosed |
| US-20040116503-A1 | Indole derivatives useful for the treatment of diseases | PFIZER INC. | 2004-06-17 | — | — | US | disclosed |
| WO-2004032921-A1 | INDOLE DERIVATIVES AS BETA-2 AGONISTS | PFIZER LIMITED (GB) | 2004-04-22 | — | — | WO | disclosed |
| US-20040063643-A1 | Bombesin antagonists | PFIZER INC. | 2004-04-01 | — | — | US | disclosed |
| WO-2003092670-A1 | BOMBESIN ANTAGONISTS | WARNER-LAMBERT COMPANY LLC (US) | 2003-11-13 | — | — | WO | disclosed |
| EP-0154969-A2 | Piperazine derivatives and their acid addition salts | MITSUBISHI KASEI CORPORATION (JP) | 1985-09-18 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230271975-A1 | IMIDAZOLE-CONTAINING INHIBITORS OF ALK2 KINASE | ALK, ACVR2B, ACVR2A | ALDH1A1 980/4885HSD17B10 1857/4885HPGD 2235/4885 |
| US-11661426-B2 | Imidazole-containing inhibitors of ALK2 kinase | ALK, ACVR2B, ACVR2A | ALDH1A1 980/4885HSD17B10 1857/4885HPGD 2235/4885 |
| US-20050085526-A1 | Indole derivatives useful for the treatment of diseases | IDO1, IDO2, INMT | ALDH1A1 549/4885HSD17B10 813/4885HPGD 74/4885 |
| US-20040063643-A1 | Bombesin antagonists | BRS3, NPSR1, GNRHR | ALDH1A1 3777/4885HSD17B10 2627/4885HPGD 852/4885 |
| US-10752624-B2 | Kinase inhibitors | LRRK2, MYLK2, MYLK | ALDH1A1 4184/4885HSD17B10 4376/4885HPGD 4156/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.