Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.59 |
| ▸ | CYP3A4 | P08684 | 7/20 | 0.56 |
| ▸ | MAPT | P10636 | 1/20 | 0.56 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.48 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.48 |
| ▸ | MAOA | P21397 | 1/20 | 0.48 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.48 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.48 |
| ▸ | HTR2B | P41595 | 1/20 | 0.48 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | ACHE | P22303 | 3/20 | 0.43 |
| ▸ | CYTH2 | Q99418 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.38 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | CASP3 | P42574 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29421987 | 0.85 | CYP3A4 (0.74) | TDP1CYP3A4MAPTCHRM1ALOX15 | |
| SCHEMBL17265618 | 0.85 | CYP3A4 (0.74) | TDP1CYP3A4MAPTCHRM1ALOX15 | |
| SCHEMBL23321603 | 0.80 | TDP1 (0.45) | TDP1CYP3A4MAPTCHRM1ALOX15 | |
| SCHEMBL27598104 | 0.80 | CYP3A4 (0.50) | TDP1CYP3A4MAPTCHRM1ALOX15 | |
| SCHEMBL19596581 | 0.77 | CA1 (0.67) | TDP1CYP3A4MAPTPTPN1ALDH1A1 | |
| SCHEMBL29046678 | 0.77 | CYP3A4 (0.53) | TDP1CYP3A4MAPTALDH1A1ACHE | |
| SCHEMBL4580680 | 0.77 | NNMT (0.45) | TDP1CYP3A4MAPTALDH1A1ACHE | |
| SCHEMBL10030804 | 0.77 | ACHE (0.43) | TDP1CYP3A4MAPTALDH1A1ACHE | |
| SCHEMBL129762 | 0.77 | ACHE (0.57) | TDP1CYP3A4MAPTPTPN1ALDH1A1 | |
| SCHEMBL29421877 | 0.75 | PTPN1 (0.62) | TDP1CYP3A4MAPTALOX15PTPN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3947365-B1 | SUBSTITUTED-N-HETEROARYL COMPOUNDS AND USES THEREOF | BIONOMICS LTD (AU) | 2025-10-01 | — | — | EP | disclosed |
| EP-3819301-B1 | PREPARATION OF ORGANOSILICON COMPOUND HAVING (METH)ACRYLOYLOXY GROUP | SHINETSU CHEMICAL CO (JP) | 2025-08-06 | — | — | EP | disclosed |
| US-12371447-B2 | Method for producing (meth)acryloxy group-containing organosilicon compounds | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 2025-07-29 | — | — | US | disclosed |
| US-12139473-B2 | Substituted-N-heteroaryl compounds and uses thereof | BIONOMICS LIMITED (AU) | 2024-11-12 | — | — | US | disclosed |
| EP-4174076-B1 | METHOD FOR PRODUCING (METH)ACRYLOXY GROUP-CONTAINING ORGANOSILICON COMPOUNDS | SHINETSU CHEMICAL CO (JP) | 2024-07-24 | — | — | EP | disclosed |
| CN-116364885-A | Lithium supplementing material, preparation method thereof, positive electrode plate and secondary battery | 深圳市德方创域新能源科技有限公司 | 2023-06-30 | — | — | CN | disclosed |
| CN-116314688-A | Lithium supplementing material, preparation method thereof, positive electrode plate and secondary battery | 深圳市德方创域新能源科技有限公司 | 2023-06-23 | — | — | CN | disclosed |
| US-20230134471-A1 | METHOD FOR PRODUCING (METH)ACRYLOXY GROUP-CONTAINING ORGANOSILICON COMPOUNDS | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 2023-05-04 | — | — | US | disclosed |
| EP-4174076-A1 | METHOD FOR PRODUCING (METH)ACRYLOXY GROUP-CONTAINING ORGANOSILICON COMPOUNDS | Shin-Etsu Chemical Co., Ltd. (JP) | 2023-05-03 | — | — | EP | disclosed |
| CN-116041382-A | Method for producing organosilicon compounds containing (meth) acryloxy groups | 信越化学工业株式会社 | 2023-05-02 | — | — | CN | disclosed |
| US-20220112176-A1 | SUBSTITUTED-N-HETEROARYL COMPOUNDS AND USES THEREOF | BIONOMICS LIMITED (AU) | 2022-04-14 | — | — | US | disclosed |
| US-20220112176-A1 | SUBSTITUTED-N-HETEROARYL COMPOUNDS AND USES THEREOF | BIONOMICS LIMITED (AU) | 2022-04-14 | — | — | US | disclosed |
| EP-3947365-A2 | SUBSTITUTED-N-HETEROARYL COMPOUNDS AND USES THEREOF | Bionomics Limited (AU) | 2022-02-09 | — | — | EP | disclosed |
| US-20210139515-A1 | Preparation of Organosilicon Compound Having (Meth)acryloyloxy Group | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 2021-05-13 | — | — | US | disclosed |
| EP-3819301-A1 | PREPARATION OF ORGANOSILICON COMPOUND HAVING (METH)ACRYLOYLOXY GROUP | Shin-Etsu Chemical Co., Ltd. (JP) | 2021-05-12 | — | — | EP | disclosed |
| WO-2020000065-A2 | SUBSTITUTED-N-HETEROARYL COMPOUNDS AND USES THEREOF | BIONOMICS LIMITED (AU) | 2020-01-02 | — | — | WO | disclosed |
| WO-2020000065-A2 | SUBSTITUTED-N-HETEROARYL COMPOUNDS AND USES THEREOF | BIONOMICS LIMITED (AU) | 2020-01-02 | — | — | WO | disclosed |
| US-20180051116-A1 | PROCESS FOR PRODUCING MODIFIED THERMOSETTING POLYPHENYLENE ETHER RESIN | NAN YA PLASTICS CORPORATION (TW) | 2018-02-22 | — | — | US | disclosed |
| WO-2017083719-A1 | TRANSITION METAL FREE METHODS OF SYNTHESIS OF BIARYL COMPOUNDS | WILLIAM MARSH RICE UNIVERSITY (US) | 2017-05-18 | — | — | WO | disclosed |
| US-5071965-A | NOVEL TC-99M COMPLEXES | MALLINCKRODT MEDICAL, INC. (US) | 1991-12-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220112176-A1 | SUBSTITUTED-N-HETEROARYL COMPOUNDS AND USES THEREOF | GABRE, GRIN2C, GRIN2A | TDP1 1602/4885CYP3A4 1188/4885MAPT 383/4885 |
| US-12371447-B2 | Method for producing (meth)acryloxy group-containing organosilicon compounds | HM13, RPS13, GRHPR | TDP1 3442/4885CYP3A4 2993/4885MAPT 4369/4885 |
| US-12139473-B2 | Substituted-N-heteroaryl compounds and uses thereof | SCN3A, KCND3, GRIN3A | TDP1 1569/4885CYP3A4 2075/4885MAPT 379/4885 |
| US-20210139515-A1 | Preparation of Organosilicon Compound Having (Meth)acryloyloxy Group | H4C1; H4C2; H4C3; H4C4; H4C5; H4C6; H4C8; H4C9; H4C11; H4C12; H4C13; H4C14; H4C15; H4C16, MMAB, ACR | TDP1 3905/4885CYP3A4 2392/4885MAPT 3041/4885 |
| US-20230134471-A1 | METHOD FOR PRODUCING (METH)ACRYLOXY GROUP-CONTAINING ORGANOSILICON COMPOUNDS | HM13, RPS13, GRHPR | TDP1 3442/4885CYP3A4 2993/4885MAPT 4369/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.