Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.48 |
| ▸ | SLC6A9 | P48067 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | TFPI2 | P48307 | 1/20 | 0.35 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.33 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3987598 | 1.00 | HSD17B10 (0.48) | HSD17B10SLC6A9ALDH1A1MAPTCYP1A2 | |
| SCHEMBL5237881 | 0.98 | HSD17B10 (0.47) | HSD17B10SLC6A9ALDH1A1MAPTCYP1A2 | |
| SCHEMBL2909901 | 0.87 | HSD17B10 (0.39) | HSD17B10SLC6A9ALDH1A1MAPTCYP1A2 | |
| Tetraxetan SCHEMBL2017956 | 0.83 | HSD17B10 (0.64) | HSD17B10SLC6A9ALDH1A1MAPTCYP1A2 | |
| SCHEMBL321989 | 0.83 | HSD17B10 (0.64) | HSD17B10SLC6A9ALDH1A1MAPTCYP1A2 | |
| SCHEMBL6848102 | 0.83 | HSD17B10 (0.64) | HSD17B10SLC6A9ALDH1A1MAPTCYP1A2 | |
| Tetraxetan SCHEMBL2635294 | 0.83 | HSD17B10 (0.64) | HSD17B10SLC6A9ALDH1A1MAPTCYP1A2 | |
| SCHEMBL173508 | 0.83 | HSD17B10 (0.64) | HSD17B10SLC6A9ALDH1A1MAPTCYP1A2 | |
| Tetraxetan SCHEMBL18018 | 0.83 | HSD17B10 (0.64) | HSD17B10SLC6A9ALDH1A1MAPTCYP1A2 | |
| SCHEMBL3503521 | 0.83 | HSD17B10 (0.64) | HSD17B10SLC6A9ALDH1A1MAPTCYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 26 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0988305-B1 | A PROCESS FOR THE PREPARATION OF 5H,9bH-2a, 4a,7,9a-OCTAHYDROTETRAAZACYCLOOCTA [cd] PENTALENE | BRACCO INT BV (NL) | 2007-03-28 | — | — | EP | claimed |
| CN-116547271-A | Production method for preparing gadoteridol | 伯拉考成像股份公司 | 2023-08-04 | — | — | CN | disclosed |
| US-7351389-B2 | Aminocarboxylate ligands having substituted aromatic amide moieties | BRACCO INTERNATIONAL B.V. (NL) | 2008-04-01 | — | — | US | disclosed |
| EP-0988305-B1 | A PROCESS FOR THE PREPARATION OF 5H,9bH-2a, 4a,7,9a-OCTAHYDROTETRAAZACYCLOOCTA [cd] PENTALENE | BRACCO INT BV (NL) | 2007-03-28 | — | — | EP | disclosed |
| EP-0988294-B1 | A PROCESS FOR THE PREPARATION OF MACROCYCLIC CHELANTS AND THE CHELATES THEREOF WITH PARAMAGNETIC METAL IONS | BRACCO INT BV (NL) | 2005-11-02 | — | — | EP | disclosed |
| US-20050090689-A1 | Aminocarboxylate ligands having substituted aromatic amide moieties | BRACCO INTERNATIONAL B.V. (NL) | 2005-04-28 | — | — | US | disclosed |
| US-6875864-B2 | Aminocarboxylate ligands having substituted aromatic amide moieties | BRACCO INTERNATIONAL B.V. (NL) | 2005-04-05 | — | — | US | disclosed |
| US-20030171561-A1 | Aminocarboxylate ligands having substituted aromatic amide moieties | BRACCO SUISSE SA (CH) | 2003-09-11 | — | — | US | disclosed |
| EP-0991471-B1 | METHOD FOR THE DEIONIZATION OF SUBSTANCES THAT ARE NOT STABLE AT ACIDIC pH | BRACCO INT BV (NL) | 2003-08-27 | — | — | EP | disclosed |
| EP-0989974-B1 | A PROCESS FOR THE PREPARATION OF 1,4,7,10-TETRAAZACYCLODODECANE-1,4,7-TRIACETIC ACID AND THE DERIVATIVES THEREOF | BRACCO INT BV (NL) | 2002-09-18 | — | — | EP | disclosed |
| EP-0988305-A1 | A PROCESS FOR THE PREPARATION OF 5H,9bH-2a, 4a,7,9a-OCTAHYDROTETRAAZACYCLOOCTA cd]PENTALENE | BRACCO INTERNATIONAL B.V. (NL) | 2000-03-29 | — | — | EP | disclosed |
| US-6042810-A | Process for the preparation of macrocyclic chelants and the chelates thereof with paramagnetic metal ions | DIBRA S.P.A. (IT) | 2000-03-28 | — | — | US | disclosed |
| US-5962679-A | Process for the preparation of 1,4,7,10-tetraaza-cyclododecane-1,4,7-triacetic acid and the derivatives thereof | DIBRA S.P.A. (IT) | 1999-10-05 | — | — | US | disclosed |
| US-5925753-A | Process for the preparation of 5H, 9bH-2a, 4a, 7, 9a-octahydro-tetraazacycloocta cd!pentalene | DIBRA S.P.A. (IT) | 1999-07-20 | — | — | US | disclosed |
| US-5925752-A | Process for the preparation of macrocyclic chelants and the chelates thereof with paramagnetic metal ions | DIBRA S.P.A. (IT) | 1999-07-20 | — | — | US | disclosed |
| WO-1998056504-A1 | METHOD FOR THE DEIONIZATION OF SUBSTANCES THAT ARE NOT STABLE AT ACIDIC pH | BRACCO S.P.A. (IT) | 1998-12-17 | — | — | WO | disclosed |
| WO-1998056791-A1 | A PROCESS FOR THE PREPARATION OF 5H,9bH-2a, 4a,7,9a-OCTAHYDROTETRAAZACYCLOOCTA [cd]PENTALENE | BRACCO S.P.A. (IT) | 1998-12-17 | — | — | WO | disclosed |
| US-5573752-A | Aromatic amide compounds and metal chelates thereof | BRACCO INTERNATIONAL B.V. | 1996-11-12 | — | — | US | disclosed |
| EP-0702677-A1 | AROMATIC AMIDE COMPOUNDS AND METAL CHELATES THEREOF | BRACCO International B.V. (NL) | 1996-03-27 | — | — | EP | disclosed |
| WO-1995027705-A1 | AROMATIC AMIDE COMPOUNDS AND METAL CHELATES THEREOF | BRACCO INTERNATIONAL B.V. (NL) | 1995-10-19 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030171561-A1 | Aminocarboxylate ligands having substituted aromatic amide moieties | ARGLU1, PRMT1, AADAC | HSD17B10 4364/4885SLC6A9 1383/4885ALDH1A1 741/4885 |
| US-20050090689-A1 | Aminocarboxylate ligands having substituted aromatic amide moieties | AADAC, ANXA3, AAAS | HSD17B10 4486/4885SLC6A9 1443/4885ALDH1A1 691/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.