SCHEMBL4580916

SCHEMBL4580916

CCC(O)COCCOc1ccc(-c2nc(-c3ccccc3)nc(-c3ccccc3)n2)cc1

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 3/20 0.46
KDM4E B2RXH2 2/20 0.46
ALDH1A1 P00352 1/20 0.46
CYP1A2 P05177 1/20 0.46
HPGD P15428 1/20 0.46
CYP2C19 P33261 1/20 0.46
GAA P10253 1/20 0.46
POLB P06746 2/20 0.44
L3MBTL1 Q9Y468 2/20 0.43
MEN1 O00255 1/20 0.43
KMT2A Q03164 1/20 0.43
HTT P42858 1/20 0.43
CHRNB2 P17787 1/20 0.43
CHRNB4 P30926 1/20 0.43
CHRNA3 P32297 1/20 0.43
CHRNA7 P36544 1/20 0.43
CHRNA4 P43681 1/20 0.43
RARB P10826 1/20 0.42
SMN1; SMN2 Q16637 2/20 0.42
TP53 P04637 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13506305 0.88 MAOA (0.50) MAPTALDH1A1POLBMEN1KMT2A
SCHEMBL4580914 0.85 KDM4E (0.46) KDM4EALDH1A1GAAMEN1KMT2A
SCHEMBL28144790 0.81 KDM1A (0.47) MAPTKDM4EALDH1A1GAAPOLB
SCHEMBL12628222 0.80 MAPT (0.65) MAPTKDM4EALDH1A1CYP1A2HPGD
Phenol SCHEMBL28889999 0.78 RARB (0.43) MAPTKDM4EALDH1A1CYP1A2HPGD
SCHEMBL19601454 0.77 KDM4E (0.60) MAPTKDM4EALDH1A1CYP1A2HPGD
SCHEMBL17474755 0.76 USP2 (0.50) MAPTKDM4EALDH1A1CYP1A2CYP2C19
SCHEMBL14840114 0.76 LMNA (0.66) MAPTHPGDPOLBL3MBTL1HTT
SCHEMBL19932513 0.75 NPC1 (0.56) MAPTKDM4EALDH1A1CYP1A2HPGD
SCHEMBL16500062 0.75 ALDH1A1 (0.64) MAPTKDM4EALDH1A1CYP1A2HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8194210-B2 Polarizing plate protective film, polarizing plate and liquid crystal display device FUJIFILM CORPORATION (JP) 2012-06-05 US disclosed
US-20080100780-A1 POLARIZING PLATE PROTECTIVE FILM, POLARIZING PLATE AND LIQUID CRYSTAL DISPLAY DEVICE FUJIFILM CORPORATION (JP) 2008-05-01 US disclosed