SCHEMBL4580914

SCHEMBL4580914

CCC(O)COCCOc1ccccc1-c1nc(-c2ccccc2)nc(-c2ccccc2)n1

nearest known ligand 0.46

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 6/20 0.46
MEN1 O00255 3/20 0.46
KMT2A Q03164 3/20 0.46
ADRB2 P07550 7/20 0.44
ADRB1 P08588 4/20 0.44
ALDH1A1 P00352 6/20 0.43
SMN1; SMN2 Q16637 2/20 0.41
LMNA P02545 2/20 0.41
PKM P14618 1/20 0.41
GAA P10253 1/20 0.41
ALOX15 P16050 1/20 0.41
TSHR P16473 1/20 0.41
MAPK1 P28482 1/20 0.41
TDP1 Q9NUW8 1/20 0.41
MAOB P27338 1/20 0.40
HTR7 P34969 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4580916 0.85 MAPT (0.46) KDM4EMEN1KMT2AALDH1A1SMN1; SMN2
SCHEMBL4581724 0.78 MAPK1 (0.51) KDM4EMEN1KMT2AADRB2ALDH1A1
SCHEMBL79499 0.78 ADRB2 (0.46) KDM4EMEN1KMT2AADRB2ADRB1
SCHEMBL15677631 0.75 ADRB2 (0.65) KDM4EMEN1KMT2AADRB2ADRB1
SCHEMBL28131881 0.74 PDE5A (0.52) KDM4EMEN1KMT2AALDH1A1SMN1; SMN2
SCHEMBL13506305 0.74 MAOA (0.50) MEN1KMT2AADRB2ADRB1ALDH1A1
SCHEMBL6054718 0.74 ADRB2 (0.43) KDM4EMEN1KMT2AADRB2ADRB1
SCHEMBL7258451 0.73 MAOB (0.50) KDM4EADRB2ALDH1A1SMN1; SMN2LMNA
SCHEMBL8918201 0.73 MAPK1 (0.46) KDM4EMEN1KMT2AADRB2ALDH1A1
SCHEMBL12755352 0.72 LMNA (0.45) KDM4EMEN1KMT2AADRB2ADRB1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8194210-B2 Polarizing plate protective film, polarizing plate and liquid crystal display device FUJIFILM CORPORATION (JP) 2012-06-05 US disclosed
US-20080100780-A1 POLARIZING PLATE PROTECTIVE FILM, POLARIZING PLATE AND LIQUID CRYSTAL DISPLAY DEVICE FUJIFILM CORPORATION (JP) 2008-05-01 US disclosed