Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.49 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.47 |
| ▸ | CTSV | O60911 | 2/20 | 0.46 |
| ▸ | CTSL | P07711 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.43 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.43 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.43 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.43 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.43 |
| ▸ | FLT1 | P17948 | 1/20 | 0.43 |
| ▸ | FGFR3 | P22607 | 1/20 | 0.43 |
| ▸ | KDR | P35968 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 2/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL623566 | 0.88 | ALDH1A1 (0.54) | MAPTAKR1B1CTSVCTSLALDH1A1 | |
| SCHEMBL5628047 | 0.85 | KMT2A (0.56) | MAPTALDH1A1TSHRKMT2AMEN1 | |
| SCHEMBL525661 | 0.85 | PDGFRB (0.47) | MAPTALDH1A1TSHRKMT2AMEN1 | |
| SCHEMBL18878093 | 0.83 | KMT2A (0.46) | ALDH1A1KMT2AMEN1PDGFRBFGFR1 | |
| SCHEMBL1335440 | 0.83 | ALDH1A1 (0.44) | MAPTALDH1A1TSHRKMT2AMEN1 | |
| SCHEMBL1945443 | 0.83 | ALDH1A1 (0.46) | MAPTALDH1A1TSHRKMT2AMEN1 | |
| SCHEMBL3945186 | 0.83 | MEN1 (0.51) | MAPTALDH1A1TSHRKMT2AMEN1 | |
| SCHEMBL28306231 | 0.83 | ALDH1A1 (0.44) | MAPTALDH1A1TSHRKMT2AMEN1 | |
| SCHEMBL27091737 | 0.83 | HTT (0.48) | MAPTALDH1A1KMT2AMEN1HTT | |
| SCHEMBL29697071 | 0.81 | TSHR (0.57) | MAPTALDH1A1TSHRKMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-2000146-A | — | — | None | — | — | JP | disclosed |
| CN-217409785-U | Filtering and distilling equipment for synthesizing 5-nitroisophthalic acid dimethyl ester | 江西大宇医药原料有限公司 | 2022-09-13 | — | — | CN | disclosed |
| US-9006486-B2 | Synthesis of N1,N3-bis(2,3-dihydroxypropyl)-5-nitroisophthalamide | LIEBEL-FLARSHEIM COMPANY LLC (US) | 2015-04-14 | — | — | US | disclosed |
| US-20080188680-A1 | Process Improvement Using Solubility Characteristics | MALLINCKRODT INC. | 2008-08-07 | — | — | US | disclosed |
| US-7351389-B2 | Aminocarboxylate ligands having substituted aromatic amide moieties | BRACCO INTERNATIONAL B.V. (NL) | 2008-04-01 | — | — | US | disclosed |
| EP-1866274-A2 | PROCESS IMPROVEMENT USING SOLUBILITY CHARACTERISTICS | MALLINCKRODT INC. (US) | 2007-12-19 | — | — | EP | disclosed |
| WO-2006093728-A2 | PROCESS IMPROVEMENT USING SOLUBILITY CHARACTERISTICS | MALLINCKRODT INC. (US) | 2006-09-08 | — | — | WO | disclosed |
| US-6919021-B2 | Simulated activity of Protein A displayed by ligands attached to a cellulose bead surface | ACCURATE POLYMERS, LTD. (US) | 2005-07-19 | — | — | US | disclosed |
| US-20050090689-A1 | Aminocarboxylate ligands having substituted aromatic amide moieties | BRACCO INTERNATIONAL B.V. (NL) | 2005-04-28 | — | — | US | disclosed |
| US-6875864-B2 | Aminocarboxylate ligands having substituted aromatic amide moieties | BRACCO INTERNATIONAL B.V. (NL) | 2005-04-05 | — | — | US | disclosed |
| EP-1276557-A2 | SIMULATED ACTIVITY OF PROTEIN A DISPLAYED BY LIGANDS ATTACHED TO A CELLULOSE BEAD SURFACE | Accurate Polymers, Ltd. (US) | 2003-01-22 | — | — | EP | disclosed |
| EP-0543482-B1 | Aminocarboxylate ligands having substituted aromatic amide moieties | BRACCO INT BV (NL) | 2002-02-06 | — | — | EP | disclosed |
| US-20010045384-A1 | Simulated activity of protein a displayed by ligands attached to a cellulose bead surface | ACCURATE POLYMERS, LTD. | 2001-11-29 | — | — | US | disclosed |
| WO-2001083515-A2 | SIMULATED ACTIVITY OF PROTEIN A DISPLAYED BY LIGANDS ATTACHED TO A CELLULOSE BEAD SURFACE | ACCURATE POLYMERS, INC. (US) | 2001-11-08 | — | — | WO | disclosed |
| US-6002041-A | Process for preparing di-C1 - C4 -alkyl 5-nitro-isophthalates | BAYER AKTIENGESELLSCHAFT (DE) | 1999-12-14 | — | — | US | disclosed |
| US-5573752-A | Aromatic amide compounds and metal chelates thereof | BRACCO INTERNATIONAL B.V. | 1996-11-12 | — | — | US | disclosed |
| EP-0702677-A1 | AROMATIC AMIDE COMPOUNDS AND METAL CHELATES THEREOF | BRACCO International B.V. (NL) | 1996-03-27 | — | — | EP | disclosed |
| WO-1995027705-A1 | AROMATIC AMIDE COMPOUNDS AND METAL CHELATES THEREOF | BRACCO INTERNATIONAL B.V. (NL) | 1995-10-19 | — | — | WO | disclosed |
| EP-0543482-A1 | Aminocarboxylate ligands having substituted aromatic amide moieties | BRACCO INTERNATIONAL B.V. (NL) | 1993-05-26 | — | — | EP | disclosed |
| JP-H02146-A | 5-AMINO-N,N'-BIS(2,3-DISUBSTITUTED PROPYL)-2,4,6-TRIIODOISOPHTHALAMIDE | MALLINCKRODT INC | 1990-01-05 | — | — | JP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080188680-A1 | Process Improvement Using Solubility Characteristics | ADH5, ADH1A, ADH1C | MAPT 1162/4885AKR1B1 70/4885CTSV 3801/4885 |
| US-20050090689-A1 | Aminocarboxylate ligands having substituted aromatic amide moieties | AADAC, ANXA3, AAAS | MAPT 1746/4885AKR1B1 2778/4885CTSV 2133/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.