SCHEMBL4581962

SCHEMBL4581962

CC(C)C(=O)c1cc[c]c(N)c1

nearest known ligand 0.47

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 1/20 0.47
DBH P09172 1/20 0.47
GAA P10253 1/20 0.47
RECQL P46063 1/20 0.47
FFAR1 O14842 1/20 0.33
F10 P00742 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27946268 0.76 PARP1 (0.42) KDM4ERECQL
SCHEMBL444146 0.76 GABRP (0.44) KDM4EGAA
SCHEMBL8132733 0.75 KDM4E (0.44) KDM4EDBHGAARECQLFFAR1
SCHEMBL27946263 0.75 ALDH1A1 (0.35)
SCHEMBL2404955 0.74 ACHE (0.35)
SCHEMBL5453339 0.74 ATM (0.41) KDM4EGAA
SCHEMBL3883974 0.71 HSD17B3 (0.46) GAARECQL
SCHEMBL4316411 0.71 KDM4E (0.47) KDM4EDBHGAARECQLFFAR1
SCHEMBL13410609 0.71 GAA (0.57) KDM4EDBHGAARECQLFFAR1
SCHEMBL9254112 0.69 PBRM1 (0.55) KDM4EDBHGAARECQLF10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20080013173-A1 METHOD OF MANUFACTURING A POLARIZING PLATE PROTECTIVE FILM, POLARIZING PLATE PROTECTIVE FILM, POLARIZING PLATE, AND LIQUID CRYSTAL DISPLAY DEVICE KONICA MINOLTA OPTO, INC. (JP) 2008-01-17 US disclosed