Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | HTR7 | P34969 | 5/20 | 0.45 |
| ▸ | HTR1A | P08908 | 4/20 | 0.45 |
| ▸ | TNF | P01375 | 1/20 | 0.43 |
| ▸ | HTR1D | P28221 | 1/20 | 0.42 |
| ▸ | HTR1B | P28222 | 1/20 | 0.42 |
| ▸ | HTR2A | P28223 | 1/20 | 0.42 |
| ▸ | HTR2C | P28335 | 1/20 | 0.42 |
| ▸ | HTR2B | P41595 | 1/20 | 0.42 |
| ▸ | HTR6 | P50406 | 1/20 | 0.42 |
| ▸ | FEN1 | P39748 | 1/20 | 0.41 |
| ▸ | INPPL1 | O15357 | 1/20 | 0.41 |
| ▸ | BMPR1A | P36894 | 1/20 | 0.41 |
| ▸ | ACVR1B | P36896 | 1/20 | 0.41 |
| ▸ | ACVRL1 | P37023 | 1/20 | 0.41 |
| ▸ | ACVR1 | Q04771 | 1/20 | 0.41 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.40 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4582036 | 0.82 | ADRB1 (0.54) | TAAR1ALDH1A1KDM4EHTR7HTR1A | |
| SCHEMBL4582832 | 0.81 | TAAR1 (0.49) | TAAR1ALDH1A1KDM4EFEN1INPPL1 | |
| SCHEMBL9400977 | 0.81 | TAAR1 (0.64) | TAAR1ALDH1A1KDM4EHTR7HTR1A | |
| SCHEMBL15000493 | 0.79 | TAAR1 (0.55) | TAAR1ALDH1A1KDM4ETNF | |
| SCHEMBL9401046 | 0.79 | ALDH1A1 (0.57) | TAAR1ALDH1A1KDM4EHTR1DHTR2C | |
| SCHEMBL25255051 | 0.77 | ALDH1A1 (0.59) | TAAR1ALDH1A1KDM4EHPGDMAPT | |
| Hydrochloric Acid SCHEMBL20293586 | 0.76 | MAP3K11 (0.50) | ALDH1A1KDM4E | |
| SCHEMBL6783114 | 0.76 | ALDH1A1 (0.54) | TAAR1ALDH1A1KDM4EINPPL1BMPR1A | |
| SCHEMBL6782999 | 0.75 | ADRB1 (0.53) | TAAR1ALDH1A1KDM4EFEN1INPPL1 | |
| SCHEMBL9400849 | 0.72 | HTR3A (0.54) | TAAR1ALDH1A1KDM4EHTR7HTR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8362017-B2 | N-[5-chloro-2-(methyloxy)phenyl]-2-{[3-(1H-tetrazol-1-yl)phenyl]oxy}acetamide; antiproliferative agents; protein kinase inhibitors; drug screening | EXELIXIS, INC. (US) | 2013-01-29 | — | — | US | disclosed |
| CN-102498091-A | Glycine compound | ASTELLAS PHARMA INC | 2012-06-13 | — | — | CN | disclosed |
| US-20080096892-A1 | C-Kit Modulators And Methods Of Use | EXELIXIS, INC. (US) | 2008-04-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080096892-A1 | C-Kit Modulators And Methods Of Use | KIT, PRKCH, PRKCB | TAAR1 4080/4885ALDH1A1 2190/4885KDM4E 1020/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.