SCHEMBL4582039

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL4579844	0.93	IL6 (0.90)	IL6HTR2CBACE1MEN1KMT2A
	SCHEMBL4580952	0.91	IL6 (0.86)	IL6HTR2CSMN1; SMN2BACE1MEN1
	SCHEMBL4581342	0.90	IL6 (0.84)	IL6HTR2CMDM2BACE1MEN1
	SCHEMBL4581788	0.90	IL6 (1.00)	IL6HTR2CBACE1MEN1KMT2A
	SCHEMBL4134613	0.90	IL6 (0.84)	IL6HTR2CMEN1KMT2A
	SCHEMBL4135144	0.89	IL6 (0.83)	IL6HTR2CBACE1MEN1KMT2A
	SCHEMBL4126541	0.89	IL6 (0.83)	IL6HTR2CTP53MDM2PSEN1
	SCHEMBL4127299	0.89	IL6 (0.82)	IL6HTR2CSMN1; SMN2MEN1KMT2A
	SCHEMBL13639324	0.89	IL6 (0.82)	IL6HTR2CBACE1MEN1KMT2A
	SCHEMBL4579352	0.88	IL6 (0.81)	IL6HTR2C

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.