Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MKNK1 | Q9BUB5 | 3/20 | 0.59 |
| ▸ | MKNK2 | Q9HBH9 | 3/20 | 0.59 |
| ▸ | MAP4K4 | O95819 | 2/20 | 0.55 |
| ▸ | NOS3 | P29474 | 1/20 | 0.52 |
| ▸ | NOS1 | P29475 | 1/20 | 0.52 |
| ▸ | NOS2 | P35228 | 1/20 | 0.52 |
| ▸ | AKT1 | P31749 | 1/20 | 0.51 |
| ▸ | AKT2 | P31751 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | COMT | P21964 | 1/20 | 0.47 |
| ▸ | USP2 | O75604 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 2/20 | 0.46 |
| ▸ | RAB9A | P51151 | 2/20 | 0.46 |
| ▸ | SYK | P43405 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL2488216 | 0.98 | MKNK1 (0.57) | MKNK1MKNK2MAP4K4NOS3NOS1 | |
| SCHEMBL12474031 | 0.90 | MKNK1 (0.50) | MKNK1MKNK2MAP4K4NOS3NOS1 | |
| SCHEMBL623098 | 0.90 | MKNK1 (0.50) | MKNK1MKNK2MAP4K4NOS3NOS1 | |
| SCHEMBL623743 | 0.87 | MKNK1 (0.48) | MKNK1MKNK2MAP4K4NOS3NOS1 | |
| SCHEMBL623411 | 0.82 | MAP4K4 (0.61) | MKNK1MKNK2MAP4K4NOS3NOS1 | |
| SCHEMBL1148699 | 0.81 | MAP4K4 (0.66) | MKNK1MKNK2MAP4K4NOS3NOS1 | |
| SCHEMBL624668 | 0.80 | MKNK1 (0.64) | MKNK1MKNK2MAP4K4NOS3NOS1 | |
| SCHEMBL2253189 | 0.80 | MKNK1 (0.59) | MKNK1MKNK2MAP4K4NOS3NOS1 | |
| SCHEMBL4582566 | 0.80 | MKNK1 (0.59) | MKNK1MKNK2MAP4K4NOS3NOS1 | |
| SCHEMBL30128566 | 0.80 | MKNK1 (0.59) | MKNK1MKNK2MAP4K4NOS3NOS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023167049-A1 | EPOXY RESIN COMPOSITION, REINFORCING FIBER-CONTAINING EPOXY RESIN COMPOSITION, PREPREG, FIBER REINFORCED PLASTIC EMPLOYING SAME, AND THERMOPLASTIC EPOXY RESIN | 日鉄ケミカル＆マテリアル株式会社 | 2023-09-07 | — | — | WO | disclosed |
| US-8362017-B2 | N-[5-chloro-2-(methyloxy)phenyl]-2-{[3-(1H-tetrazol-1-yl)phenyl]oxy}acetamide; antiproliferative agents; protein kinase inhibitors; drug screening | EXELIXIS, INC. (US) | 2013-01-29 | — | — | US | disclosed |
| US-20080096892-A1 | C-Kit Modulators And Methods Of Use | EXELIXIS, INC. (US) | 2008-04-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080096892-A1 | C-Kit Modulators And Methods Of Use | KIT, PRKCH, PRKCB | MKNK1 417/4885MKNK2 539/4885MAP4K4 354/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.