SCHEMBL624668

SCHEMBL624668

Nc1ncccc1-c1ccc(O)cc1

nearest known ligand 0.64

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
MKNK1 Q9BUB5 1/20 0.64
MKNK2 Q9HBH9 1/20 0.64
USP7 Q93009 10/20 0.55
MAP4K4 O95819 1/20 0.55
ADORA2A P29274 1/20 0.45
ADORA1 P30542 1/20 0.45
FYN P06241 3/20 0.44
ABL1 P00519 1/20 0.44
ABCB1 P08183 1/20 0.44
BCR P11274 1/20 0.44
RPS6KA3 P51812 1/20 0.42
NOS3 P29474 1/20 0.42
NOS1 P29475 1/20 0.42
NOS2 P35228 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15104945 0.86 MKNK1 (0.50) MKNK1MKNK2USP7MAP4K4ADORA2A
SCHEMBL623411 0.82 MAP4K4 (0.61) MKNK1MKNK2USP7MAP4K4NOS3
SCHEMBL1148699 0.81 MAP4K4 (0.66) MKNK1MKNK2USP7MAP4K4NOS3
SCHEMBL623564 0.81 MKNK1 (0.60) MKNK1MKNK2USP7MAP4K4NOS3
SCHEMBL2253189 0.80 MKNK1 (0.59) MKNK1MKNK2MAP4K4ADORA2AADORA1
SCHEMBL4582566 0.80 MKNK1 (0.59) MKNK1MKNK2USP7MAP4K4ABL1
SCHEMBL30128566 0.80 MKNK1 (0.59) MKNK1MKNK2MAP4K4NOS3NOS1
SCHEMBL4582572 0.80 MKNK1 (0.59) MKNK1MKNK2MAP4K4ADORA2AADORA1
SCHEMBL26071485 0.80 MKNK1 (0.59) MKNK1MKNK2MAP4K4NOS3NOS1
SCHEMBL4400609 0.79 ABL1 (0.47) MKNK1MKNK2USP7ABL1ABCB1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 77 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-1264498-C Primary intermediates for oxidative dyeing of hair PROCTER & GAMBLE (US) 2006-07-19 CN claimed
CN-1239467-C Primary intermediates for oxidative dyeing of hair P & G CLAIROL INC (US) 2006-02-01 CN claimed
CN-1229100-C Primary intermediates for oxidative dyeing of hair P & G CLAIROL INC (US) 2005-11-30 CN claimed
CN-1229102-C Novel couplers for oxidative hair dyeing P & G CLAIROL INC (US) 2005-11-30 CN claimed
CN-1219501-C Primary intermediates for oxidative dyeing of hair P & G CLAIROL INCORP (US) 2005-09-21 CN claimed
CN-1213722-C Couplers for oxidative hair dyeing P & G CLAIROL INC (US) 2005-08-10 CN claimed
CN-1198574-C Novel couplers for oxidative hair dyeing P & G CLAIROL INC (US) 2005-04-27 CN claimed
CN-1607935-A Primary intermediates for oxidative dyeing of hair PROCTER & GAMBLE (US) 2005-04-20 CN claimed
CN-1503657-A Novel couplers for oxidative hair dyeing P&G 2004-06-09 CN claimed
CN-1501792-A Novel couplers for oxidative hair dyeing P&G克莱罗尔公司 2004-06-02 CN claimed
CN-1487815-A Novel couplers for use in oxidative hair dyeing P&G 2004-04-07 CN claimed
CN-1486172-A Primary intermediates for oxidative dyeing of hair P&G 2004-03-31 CN claimed
CN-1486297-A Primary intermediates for oxidative dyeing of hair P&G 2004-03-31 CN claimed
CN-1486170-A Novel couplers for use in oxidative hair dyeing P&G 2004-03-31 CN claimed
CN-1486171-A Couplers for oxidative hair dyeing P&G克莱罗尔公司 2004-03-31 CN claimed
CN-1477947-A Primary intermediates for oxidative dyeing of hair P&G 2004-02-25 CN claimed
CN-1474680-A Novel couplers for oxidative hair dyeing P&G克莱罗尔公司 2004-02-11 CN claimed
CN-1474679-A Novel couplers for oxidative hair dyeing P&G 2004-02-11 CN claimed
CN-1474681-A Novel couplers for oxidative hair dyeing P&G克莱罗尔公司 2004-02-11 CN claimed
CN-1449276-A Primary intermediates for oxidative dyeing of hair P & G CLAIROL INC (US) 2003-10-15 CN claimed