Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | CES2 | O00748 | 1/20 | 0.37 |
| ▸ | CES1 | P23141 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27864039 | 0.89 | SMN1; SMN2 (0.40) | SMN1; SMN2TSHRCES2CES1MEN1 | |
| SCHEMBL18393827 | 0.88 | SMN1; SMN2 (0.42) | SMN1; SMN2TSHRCES2CES1MEN1 | |
| SCHEMBL6140455 | 0.79 | SMN1; SMN2 (0.38) | SMN1; SMN2TSHRCES2CES1MEN1 | |
| SCHEMBL5076184 | 0.79 | SMN1; SMN2 (0.42) | SMN1; SMN2TSHRCES2CES1MEN1 | |
| SCHEMBL9344460 | 0.78 | ALDH1A1 (0.35) | SMN1; SMN2TSHR | |
| SCHEMBL1657 | 0.77 | CES2 (0.48) | SMN1; SMN2TSHRCES2CES1MEN1 | |
| SCHEMBL19307720 | 0.77 | CES2 (0.48) | SMN1; SMN2TSHRCES2CES1MEN1 | |
| SCHEMBL7995704 | 0.76 | TSHR (0.32) | SMN1; SMN2TSHR | |
| SCHEMBL6538271 | 0.75 | CES2 (0.46) | SMN1; SMN2TSHRCES2CES1HTT | |
| SCHEMBL996758 | 0.74 | CES2 (0.43) | SMN1; SMN2CES2CES1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8530269-B2 | Manufacture of a polymer device | CAMBRIDGE ENTERPRISE LTD (GB) | 2013-09-10 | — | — | US | disclosed |
| EP-1631995-B1 | MANUFACTURE OF A POLYMER DEVICE | CAMBRIDGE ENTPR LTD (GB) | 2008-07-16 | — | — | EP | disclosed |
| US-20070172978-A1 | Manufacture of a polymer device | CAMBRIDGE UNIVERSITY TECHNICAL SERVICE LIMITED (GB) | 2007-07-26 | — | — | US | disclosed |