SCHEMBL7995704

SCHEMBL7995704

O=C(Cl)c1c(F)c(C(F)(F)F)c2c(F)c(C(=O)Cl)c(F)c(C(F)(F)F)c2c1F

nearest known ligand 0.32

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
TSHR P16473 1/20 0.32
SMN1; SMN2 Q16637 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27864039 0.83 SMN1; SMN2 (0.40) TSHRSMN1; SMN2
SCHEMBL18393827 0.82 SMN1; SMN2 (0.42) TSHRSMN1; SMN2
SCHEMBL7717693 0.80 SMN1; SMN2 (0.37) TSHRSMN1; SMN2
Hydrochloric Acid SCHEMBL7995707 0.78 TSHR (0.36) TSHRSMN1; SMN2
SCHEMBL9344460 0.76 ALDH1A1 (0.35) TSHRSMN1; SMN2
SCHEMBL4582632 0.76 SMN1; SMN2 (0.37) TSHRSMN1; SMN2
SCHEMBL7718847 0.75 TSHR (0.34) TSHRSMN1; SMN2
SCHEMBL7999660 0.74 CES2 (0.37)
SCHEMBL8926676 0.74 CA1 (0.36) TSHRSMN1; SMN2
SCHEMBL996758 0.72 CES2 (0.43) SMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6297351-B1 EXCELLENT IN ELECTRIC CHARACTERISTICS AND HEAT RESISTANCE, PRECURSOR FROM A DICARBOXYLIC ACID AND A BISAMINOPHENOL COMPOUND OR A DIAMINODIHYDROXY SUMITOMO BAKELITE COMPANY LIMITED (JP) 2001-10-02 US disclosed