Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.60 |
| ▸ | LMNA | P02545 | 1/20 | 0.60 |
| ▸ | CTSL | P07711 | 3/20 | 0.60 |
| ▸ | CTSS | P25774 | 3/20 | 0.60 |
| ▸ | CTSB | P07858 | 2/20 | 0.60 |
| ▸ | MME | P08473 | 1/20 | 0.54 |
| ▸ | ECE1 | P42892 | 1/20 | 0.54 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.53 |
| ▸ | CTSK | P43235 | 1/20 | 0.53 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.53 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.53 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.53 |
| ▸ | RAB9A | P51151 | 1/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | CASP3 | P42574 | 1/20 | 0.48 |
| ▸ | ANPEP | P15144 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23086206 | 1.00 | MEN1 (0.60) | MEN1KMT2ALMNACTSLCTSS | |
| SCHEMBL23086208 | 1.00 | MEN1 (0.60) | MEN1KMT2ALMNACTSLCTSS | |
| SCHEMBL4582904 | 0.89 | MAPK1 (0.53) | MEN1KMT2ALMNACTSLCTSS | |
| SCHEMBL4582911 | 0.89 | MAPK1 (0.53) | MEN1KMT2ALMNACTSLCTSS | |
| SCHEMBL919245 | 0.89 | MAPK1 (0.53) | MEN1KMT2ALMNACTSLCTSS | |
| SCHEMBL24734375 | 0.87 | CTSL (0.71) | MEN1KMT2ALMNACTSLCTSS | |
| SCHEMBL221435 | 0.87 | CTSL (0.71) | MEN1KMT2ALMNACTSLCTSS | |
| SCHEMBL5145628 | 0.87 | CTSL (0.71) | MEN1KMT2ALMNACTSLCTSS | |
| SCHEMBL7264750 | 0.87 | CTSL (0.71) | MEN1KMT2ALMNACTSLCTSS | |
| SCHEMBL8837344 | 0.87 | CTSL (0.71) | MEN1KMT2ALMNACTSLCTSS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4077353-B1 | SYNTHESIS OF AMANIN AND ITS DERIVATIVES | HEIDELBERG PHARMA RES GMBH (DE) | 2025-04-23 | — | — | EP | disclosed |
| US-20230039142-A1 | SYNTHESIS OF AMANIN AND ITS DERIVATIVES | HEIDELBERG PHARMA RESEARCH GMBH (DE) | 2023-02-09 | — | — | US | disclosed |
| EP-4077353-A1 | SYNTHESIS OF AMANIN AND ITS DERIVATIVES | Heidelberg Pharma Research GmbH (DE) | 2022-10-26 | — | — | EP | disclosed |
| US-20220298204-A1 | SYNTHESIS OF A-AMANITIN AND ITS DERIVATIVES | PURE BIOORGANICS SIA (LV) | 2022-09-22 | — | — | US | disclosed |
| WO-2021122744-A1 | SYNTHESIS OF AMANIN AND ITS DERIVATIVES | HEIDELBERG PHARMA RESEARCH GMBH (DE) | 2021-06-24 | — | — | WO | disclosed |
| EP-3792250-A1 | SYNTHESIS OF ALPHA-AMANITIN AND ITS DERIVATIVES | Pure Bioorganics SIA (LV) | 2021-03-17 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220298204-A1 | SYNTHESIS OF A-AMANITIN AND ITS DERIVATIVES | MEP1A, MEP1B, MANBA | MEN1 124/4885KMT2A 2218/4885LMNA 2039/4885 |
| US-20230039142-A1 | SYNTHESIS OF AMANIN AND ITS DERIVATIVES | AANAT, TYR, CIAPIN1 | MEN1 15/4885KMT2A 1468/4885LMNA 3161/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.