⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bromide SCHEMBL640020 | 0.98 | — | — | |
| Hydrochloric Acid SCHEMBL640861 | 0.98 | — | — | |
| SCHEMBL17099921 | 0.75 | ALDH1A1 (0.48) | — | |
| SCHEMBL30957 | 0.73 | — | — | |
| SCHEMBL13301118 | 0.73 | — | — | |
| SCHEMBL360323 | 0.71 | — | — | |
| SCHEMBL4984891 | 0.71 | — | — | |
| SCHEMBL550353 | 0.71 | — | — | |
| SCHEMBL22577271 | 0.71 | — | — | |
| SCHEMBL12151092 | 0.71 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 495 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-2006504796-A | — | — | 2006-02-09 | — | — | JP | claimed |
| EP-1551815-A1 | THIAZOLE COMPOUNDS FOR THE TREATMENT OF NEURODEGENERATIVE DISORDERS | Pfizer Products Inc. (US) | 2005-07-13 | — | — | EP | claimed |
| US-20040152747-A1 | Thiazole compounds for treatment of neurodegenerative disorders | PFIZER INC | 2004-08-05 | — | — | US | claimed |
| WO-2004033439-A1 | THIAZOLE COMPOUNDS FOR THE TREATMENT OF NEURODEGENERATIVE DISORDERS | PFIZER PRODUCTS INC. (US) | 2004-04-22 | — | — | WO | claimed |
| US-4324899-A | 2-Amino-5-cyanothiazoles and their preparation | EASTMAN KODAK COMPANY (US) | 1982-04-13 | — | — | US | claimed |
| US-4225719-A | Process for preparing 2-amino-5-formylthiazole and its hydrobromide salt | EASTMAN KODAK COMPANY (US) | 1980-09-30 | — | — | US | claimed |
| CN-116003441-B | Heteroaromatic derivative regulator, preparation method and application thereof | 江苏豪森药业集团有限公司 | 2025-06-10 | — | — | CN | disclosed |
| CN-116535386-B | Cyanoethylene sulfonyl anilide compound and preparation method and medical application thereof | 西南大学 | 2025-05-27 | — | — | CN | disclosed |
| US-12275728-B2 | O-glycoprotein-2-acetamido-2-deoxy-3-D-glucopyranosidase inhibitors | BIOGEN MA INC. (US) | 2025-04-15 | — | — | US | disclosed |
| CN-115925705-B | Heteroaromatic derivative regulator, preparation method and application thereof | 江苏豪森药业集团有限公司 | 2024-12-31 | — | — | CN | disclosed |
| US-12180205-B2 | O-glycoprotein-2-acetamido-2-deoxy-3-d-glucopyranosidase inhibitors | BIOGEN MA INC. (US) | 2024-12-31 | — | — | US | disclosed |
| US-20240383898-A1 | PYRIDO RING COMPOUND, PREPARATION METHOD THEREFOR, INTERMEDIATE, COMPOSITION, AND APPLICATION | YIYOU BIOTECH (SHANGHAI) CO., LTD. (CN) | 2024-11-21 | — | — | US | disclosed |
| US-20240308995-A1 | O-GLYCOPROTEIN-2-ACETAMIDO-2-DEOXY-3-D-GLUCOPYRANOSIDASE INHIBITORS | BIOGEN MA INC. | 2024-09-19 | — | — | US | disclosed |
| EP-0702683-A1 | 06-SUBSTITUTED GUANINE DERIVATIVES, A PROCESS FOR THEIR PREPARATION AND THEIR USE IN TREATING TUMOUR CELLS | CANCER RESEARCH CAMPAIGN TECHNOLOGY LIMITED (GB) | 1996-03-27 | — | — | EP | disclosed |
| WO-1994029312-A1 | O6-SUBSTITUTED GUANINE DERIVATIVES, A PROCESS FOR THEIR PREPARATION AND THEIR USE IN TREATING TUMOUR CELLS | CANCER RESEARCH CAMPAIGN TECHNOLOGY LIMITED (GB) | 1994-12-22 | — | — | WO | disclosed |
| US-4324899-A | 2-Amino-5-cyanothiazoles and their preparation | EASTMAN KODAK COMPANY (US) | 1982-04-13 | — | — | US | disclosed |
| US-4324899-A | 2-Amino-5-cyanothiazoles and their preparation | EASTMAN KODAK COMPANY (US) | 1982-04-13 | — | — | US | disclosed |
| US-4225719-A | Process for preparing 2-amino-5-formylthiazole and its hydrobromide salt | EASTMAN KODAK COMPANY (US) | 1980-09-30 | — | — | US | disclosed |
| US-4225719-A | Process for preparing 2-amino-5-formylthiazole and its hydrobromide salt | EASTMAN KODAK COMPANY (US) | 1980-09-30 | — | — | US | disclosed |
| US-4225719-A | Process for preparing 2-amino-5-formylthiazole and its hydrobromide salt | EASTMAN KODAK COMPANY (US) | 1980-09-30 | — | — | US | disclosed |