Known targets — ChEMBL curated mechanism
ACHEADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3APH1AAPH1BCHRM2CHRM3EZH2GRIN2AHTR1AHTR1BHTR1DHTR1FHTR3ANCSTNP2RY12PSEN1PSEN2PSENENSIGMAR1SLC6A2SLC6A3SLC6A4
The experimentally established mechanism targets of Bromide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL458299 | 0.98 | — | — | |
| Hydrochloric Acid SCHEMBL640861 | 0.95 | — | — | |
| SCHEMBL17099921 | 0.73 | ALDH1A1 (0.48) | — | |
| SCHEMBL30957 | 0.71 | — | — | |
| SCHEMBL13301118 | 0.71 | — | — | |
| SCHEMBL360323 | 0.70 | — | — | |
| SCHEMBL4984891 | 0.70 | — | — | |
| SCHEMBL550353 | 0.70 | — | — | |
| SCHEMBL22577271 | 0.70 | — | — | |
| SCHEMBL12151092 | 0.70 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4225719-A | Process for preparing 2-amino-5-formylthiazole and its hydrobromide salt | EASTMAN KODAK COMPANY (US) | 1980-09-30 | — | — | US | claimed |
| US-8119626-B2 | Oxime derivative and preparations thereof | MITSUBISHI TANABE PHARMA CORPORATION (JP) | 2012-02-21 | — | — | US | disclosed |
| US-20090291936-A1 | OXIME DERIVATIVE AND PREPARATIONS THEREOF | SUGAWARA KAZUTOSHI | 2009-11-26 | — | — | US | disclosed |
| US-7514439-B2 | Oxime derivative and preparations thereof | MITSUBISHI TANABE PHARMA CORPORATION (JP) | 2009-04-07 | — | — | US | disclosed |
| US-20080132479-A1 | Oxime Derivative and Preparations Thereof | MITSUBISHI TANABE PHARMA CORPORATION (JP) | 2008-06-05 | — | — | US | disclosed |
| EP-1907387-A1 | AN OXIME DERIVATIVE AND PREPARATIONS THEREOF | Mitsubishi Tanabe Pharma Corporation (JP) | 2008-04-09 | — | — | EP | disclosed |
| WO-2007007886-A1 | AN OXIME DERIVATIVE AND PREPARATIONS THEREOF | MITSUBISHI TANABE PHARMA CORPORATION (JP) | 2007-01-18 | — | — | WO | disclosed |
| EP-0873324-A1 | IMPROVED PROCESS FOR PRODUCING 5-FORMYLTHIAZOL | BAYER AG (DE) | 1998-10-28 | — | — | EP | disclosed |
| WO-1997022599-A1 | IMPROVED PROCESS FOR PRODUCING 5-FORMYLTHIAZOL | BAYER AKTIENGESELLSCHAFT (DE) | 1997-06-26 | — | — | WO | disclosed |
| US-4324899-A | 2-Amino-5-cyanothiazoles and their preparation | EASTMAN KODAK COMPANY (US) | 1982-04-13 | — | — | US | disclosed |
| US-4225719-A | Process for preparing 2-amino-5-formylthiazole and its hydrobromide salt | EASTMAN KODAK COMPANY (US) | 1980-09-30 | — | — | US | disclosed |
| US-4225719-A | Process for preparing 2-amino-5-formylthiazole and its hydrobromide salt | EASTMAN KODAK COMPANY (US) | 1980-09-30 | — | — | US | disclosed |