Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD1 | P21728 | 2/20 | 0.38 |
| ▸ | PARP1 | P09874 | 2/20 | 0.35 |
| ▸ | PBRM1 | Q86U86 | 3/20 | 0.35 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.35 |
| ▸ | CACNG8 | Q8WXS5 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.35 |
| ▸ | GUSB | P08236 | 1/20 | 0.34 |
| ▸ | AR | P10275 | 1/20 | 0.33 |
| ▸ | P2RX7 | Q99572 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | TYMS | P04818 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | CES1 | P23141 | 1/20 | 0.32 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.32 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.32 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.32 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4583927 | 0.77 | TYMP (0.47) | DRD1HSD17B10CHEK1KMT2AGRIN2D | |
| SCHEMBL4582481 | 0.75 | NPSR1 (0.36) | DRD1PARP1PBRM1GRIA1CACNG8 | |
| SCHEMBL4583123 | 0.73 | DRD1 (0.35) | DRD1 | |
| SCHEMBL896720 | 0.70 | TGFBR1 (0.49) | HSD17B10KMT2ASMN1; SMN2 | |
| SCHEMBL3848168 | 0.69 | P2RX7 (0.41) | PBRM1P2RX7KMT2ASMN1; SMN2 | |
| SCHEMBL2352712 | 0.69 | PTGES (0.43) | GRIA1CACNG8CHEK1P2RX7KMT2A | |
| SCHEMBL25999784 | 0.68 | NOS3 (0.48) | — | |
| SCHEMBL1871032 | 0.66 | PTGES (0.38) | DRD1GRIA1CACNG8P2RX7 | |
| SCHEMBL14310776 | 0.65 | AR (0.49) | PARP1CHEK1ARTYMS | |
| SCHEMBL4584726 | 0.64 | TYMP (0.45) | DRD1HSD17B10KMT2ASMN1; SMN2GRIN2D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1972623-A1 | Arylpyridazines as fungicides | Bayer CropScience AG (DE) | 2008-09-24 | — | — | EP | disclosed |