Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 2/20 | 0.41 |
| ▸ | HTR2B | P41595 | 2/20 | 0.41 |
| ▸ | HTR6 | P50406 | 1/20 | 0.41 |
| ▸ | SSTR4 | P31391 | 3/20 | 0.40 |
| ▸ | SSTR1 | P30872 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | JAK2 | O60674 | 1/20 | 0.39 |
| ▸ | JAK3 | P52333 | 1/20 | 0.39 |
| ▸ | PTK2 | Q05397 | 1/20 | 0.39 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.38 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.37 |
| ▸ | HTR1A | P08908 | 1/20 | 0.37 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL131674 | 0.79 | HTR1A (0.51) | HTR1AHTR2C | |
| SCHEMBL26971374 | 0.79 | HTR6 (0.46) | HTR2AHTR2BHTR6SSTR4SSTR1 | |
| SCHEMBL29353268 | 0.79 | HTR6 (0.46) | HTR2AHTR2BHTR6SSTR4SSTR1 | |
| SCHEMBL17477141 | 0.78 | HTR1D (0.43) | HTR2AHTR2BHTR6SSTR4SSTR1 | |
| SCHEMBL17001658 | 0.75 | SSTR4 (0.51) | SSTR4SSTR1HTR1AHTR1F | |
| SCHEMBL29961897 | 0.74 | SSTR4 (0.42) | HTR2AHTR2BHTR6SSTR4SSTR1 | |
| SCHEMBL20473477 | 0.72 | CHRM4 (0.48) | OPRM1CHRM2 | |
| SCHEMBL17477167 | 0.72 | HTR6 (0.41) | HTR2AHTR2BHTR6SSTR4SSTR1 | |
| SCHEMBL3584144 | 0.70 | GAA (0.42) | HTR2AHTR2BHTR6CHRM2CHRM1 | |
| SCHEMBL30909178 | 0.69 | HTR1F (0.65) | HTR2AHTR6CYP1A2HTR1ACYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1972623-A1 | Arylpyridazines as fungicides | Bayer CropScience AG (DE) | 2008-09-24 | — | — | EP | disclosed |