Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1D | P28221 | 2/20 | 0.43 |
| ▸ | HTR1B | P28222 | 2/20 | 0.43 |
| ▸ | HTR1F | P30939 | 1/20 | 0.43 |
| ▸ | HTR2A | P28223 | 2/20 | 0.43 |
| ▸ | HTR2B | P41595 | 2/20 | 0.43 |
| ▸ | HTR6 | P50406 | 2/20 | 0.43 |
| ▸ | SSTR4 | P31391 | 2/20 | 0.42 |
| ▸ | SSTR1 | P30872 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.42 |
| ▸ | HTR1A | P08908 | 1/20 | 0.42 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.42 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.42 |
| ▸ | DRD1 | P21728 | 1/20 | 0.42 |
| ▸ | HTR2C | P28335 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30469945 | 0.84 | PDK2 (0.46) | CYP1A2HTR1AADRA2ACYP2D6TSHR | |
| SCHEMBL934667 | 0.84 | PDK2 (0.46) | CYP1A2HTR1AADRA2ACYP2D6TSHR | |
| SCHEMBL31316641 | 0.83 | HRH3 (0.38) | CHRM2CYP2D6CHRM1NOS3NOS1 | |
| Potassium SCHEMBL29930626 | 0.82 | PDK2 (0.45) | CYP1A2HTR1AADRA2ACYP2D6TSHR | |
| SCHEMBL26971374 | 0.81 | HTR6 (0.46) | HTR2AHTR2BHTR6SSTR4SSTR1 | |
| SCHEMBL29353268 | 0.81 | HTR6 (0.46) | HTR2AHTR2BHTR6SSTR4SSTR1 | |
| SCHEMBL5954915 | 0.80 | NOS1 (0.42) | HTR1ANOS3NOS1NOS2 | |
| SCHEMBL28763152 | 0.80 | NOS3 (0.42) | HTR1ANOS3NOS1NOS2 | |
| SCHEMBL2718434 | 0.79 | CYP11B2 (0.43) | HTR1AGAASMN1; SMN2NOS3NOS1 | |
| SCHEMBL4583160 | 0.78 | HTR2A (0.41) | HTR1FHTR2AHTR2BHTR6SSTR4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119421884-A | Polymorphic compounds and uses thereof | 普莱鲁德疗法有限公司 | 2025-02-11 | — | — | CN | disclosed |
| CN-116940563-A | CDK inhibitors and their use as pharmaceuticals | 普莱鲁德疗法有限公司 | 2023-10-24 | — | — | CN | disclosed |
| WO-2023178547-A1 | POLYMORPHIC COMPOUNDS AND USES THEREOF | PRELUDE THERAPEUTICS, INCORPORATED (US) | 2023-09-28 | — | — | WO | disclosed |
| CN-116583283-A | CDK inhibitors and their use as pharmaceuticals | 普莱鲁德疗法有限公司 | 2023-08-11 | — | — | CN | disclosed |
| WO-2016015605-A1 | COMPOUNDS AS CDK SMALL-MOLECULE INHIBITORS AND USES THEREOF | SUNSHINE LAKE PHARMA CO., LTD. (CN) | 2016-02-04 | — | — | WO | disclosed |