Known targets — ChEMBL curated mechanism
AGTR1DHFRGABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGARTNR3C2PBP2XPTGS1PTGS2VKORC1blablaT-3blaT-4blaT-5blaT-6dacAdacBdacCfolAftsImrcAmrcBmrdApbp1apbp1bpbp2apbp2bpbp3polthyA
The experimentally established mechanism targets of Potassium Ion. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.67 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.67 |
| ▸ | CA5A | P35218 | 1/20 | 0.46 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 3/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Potassium Ion SCHEMBL17457311 | 0.94 | MEN1 (0.60) | MEN1KMT2ACA5ACA5BTSHR | |
| Potassium Ion SCHEMBL1332309 | 0.94 | — | — | |
| Potassium Ion SCHEMBL10443095 | 0.94 | MEN1 (0.75) | MEN1KMT2ACA5ACA5BTSHR | |
| Potassium Ion SCHEMBL27593062 | 0.94 | MEN1 (0.75) | MEN1KMT2ACA5ACA5BTSHR | |
| Potassium Ion SCHEMBL22826 | 0.94 | — | — | |
| SCHEMBL9488141 | 0.94 | MEN1 (0.75) | MEN1KMT2ACA5ACA5BTSHR | |
| Potassium Ion SCHEMBL1330744 | 0.94 | — | — | |
| SCHEMBL71957 | 0.94 | — | — | |
| Potassium Ion SCHEMBL8666799 | 0.94 | MEN1 (0.75) | MEN1KMT2ACA5ACA5BTSHR | |
| SCHEMBL5907912 | 0.88 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108675652-A | A kind of ultra-thin chemically reinforced glass and preparation method thereof | 吴江金刚玻璃科技有限公司 | 2018-10-19 | — | — | CN | disclosed |
| EP-1536990-B1 | INFLATOR | AUTOMOTIVE SYSTEMS LAB (US) | 2008-07-16 | — | — | EP | disclosed |
| EP-1278662-B1 | INFLATOR | AUTOMOTIVE SYSTEMS LAB (US) | 2008-03-12 | — | — | EP | disclosed |
| US-7097203-B2 | Inflator | AUTOMOTIVE SYSTEMS LABORATORY, INC. (US) | 2006-08-29 | — | — | US | disclosed |
| EP-1536990-A4 | INFLATOR | AUTOMOTIVE SYSTEMS LAB (US) | 2006-05-03 | — | — | EP | disclosed |
| EP-1536990-A2 | INFLATOR | AUTOMOTIVE SYSTEMS LABORATORY INC. (US) | 2005-06-08 | — | — | EP | disclosed |
| EP-1278662-A4 | INFLATOR | AUTOMOTIVE SYSTEMS LAB (US) | 2005-06-01 | — | — | EP | disclosed |
| US-6805377-B2 | Inflator | AUTOMOTIVE SYSTEMS LABORATORY, INC. | 2004-10-19 | — | — | US | disclosed |
| US-20040084885-A1 | Inflator | AUTOMOTIVE SYSTEMS LABORATORY, INC. | 2004-05-06 | — | — | US | disclosed |
| WO-2004024503-A2 | INFLATOR | AUTOMOTIVE SYSTEMS LABORATORY, INC. (US) | 2004-03-25 | — | — | WO | disclosed |
| EP-1278662-A1 | INFLATOR | AUTOMOTIVE SYSTEMS LABORATORY INC. (US) | 2003-01-29 | — | — | EP | disclosed |
| US-20010045735-A1 | Inflator | AUTOMOTIVE SYSTEMS LABORATORY, INC. | 2001-11-29 | — | — | US | disclosed |
| WO-2001083274-A1 | INFLATOR | AUTOMOTIVE SYSTEMS LABORATORY, INC. (US) | 2001-11-08 | — | — | WO | disclosed |