SCHEMBL4583910

SCHEMBL4583910

CC(C)(C)OC(=O)CCC=O

nearest known ligand 0.42

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
HDAC6 Q9UBN7 3/20 0.42
HDAC1 Q13547 2/20 0.42
HDAC2 Q92769 2/20 0.42
HDAC3 O15379 1/20 0.42
HDAC8 Q9BY41 1/20 0.42
CTSK P43235 3/20 0.36
CA12 O43570 1/20 0.34
CA2 P00918 1/20 0.34
CA14 Q9ULX7 1/20 0.34
STING1 Q86WV6 1/20 0.33
EPHX2 P34913 1/20 0.33
CYP2D6 P10635 1/20 0.33
HPGD P15428 1/20 0.32
DGAT1 O75907 1/20 0.32
ALDH1A1 P00352 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL30639492 0.98 HDAC6 (0.41) HDAC6HDAC1HDAC2HDAC3HDAC8
SCHEMBL28515816 0.88 HDAC6 (0.38) HDAC6HDAC1HDAC2HDAC3HDAC8
SCHEMBL8223754 0.87 HDAC6 (0.40) HDAC6HDAC1HDAC2HDAC3HDAC8
SCHEMBL17309612 0.85 ALDH1A1 (0.40) HDAC6HDAC1HDAC2HDAC3HDAC8
SCHEMBL19292207 0.84 ALDH1A1 (0.43) HDAC6HDAC1HDAC2HDAC3HDAC8
SCHEMBL31110583 0.84 ALDH1A1 (0.43) HDAC6HDAC1HDAC2HDAC3HDAC8
SCHEMBL31240161 0.84 ALDH1A1 (0.43) HDAC6HDAC1HDAC2HDAC3HDAC8
SCHEMBL9431001 0.84 ALDH1A1 (0.43) HDAC6HDAC1HDAC2HDAC3HDAC8
SCHEMBL31211601 0.84 ALDH1A1 (0.43) HDAC6HDAC1HDAC2HDAC3HDAC8
SCHEMBL30864371 0.84 ALDH1A1 (0.43) HDAC6HDAC1HDAC2HDAC3HDAC8

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 168 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109715167-A Lipid-substituted amino 1, 2-and 1, 3-diol compounds as modulators of TLR2 dimerization 神经孔疗法股份有限公司 2019-05-03 CN claimed
US-20140309192-A1 MODULATORS OF THE G PROTEIN-COUPLED MAS RECEPTOR AND THE TREATMENT OF DISORDERS RELATED THERETO ARENA PHARMACEUTICALS, INC, 2014-10-16 US claimed
CN-104105691-A MODULATORS OF THE G PROTEIN-COUPLED MAS RECEPTOR AND THE TREATMENT OF DISORDERS RELATED THERETO ARENA PHARM INC 2014-10-15 CN claimed
US-20250382264-A1 HETEROCYCLE-CONTAINING AMINO ACID COMPOUND AND COMPLEX AICHI STEEL CORPORATION (JP) 2025-12-18 US disclosed
EP-3650464-B1 PEPTIDE COMPOUND AND APPLICATION THEREOF, AND COMPOSITION CONTAINING PEPTIDE COMPOUND SHANGPHARMA INNOVATION INC (US) 2025-11-05 EP disclosed
EP-4565585-A1 COMPOUNDS FOR MODULATING RET PROTEIN Bristol-Myers Squibb Company (US) 2025-06-11 EP disclosed
CN-119504710-A PROTACs compound for targeted degradation of PRMT5 and application thereof 昆明医科大学 2025-02-25 CN disclosed
EP-4501909-A1 HETEROCYCLE-CONTAINING AMINO ACID COMPOUND AND COMPLEX Aichi Steel Corporation (JP) 2025-02-05 EP disclosed
CN-118063391-A Pyrimidine compound and synthetic method and application thereof 云南民族大学 2024-05-24 CN disclosed
WO-2024030968-A1 COMPOUNDS FOR MODULATING RET PROTEIN BRYSTOL-MYERS SQUIBB COMPANY (US) 2024-02-08 WO disclosed
US-20230398225-A1 PD-L1/STING CONJUGATES AND METHODS OF USE INCYTE CORPORATION 2023-12-14 US disclosed
EP-0604368-A1 Anti retroviral hydrazine derivatives CIBA-GEIGY AG (CH) 1994-06-29 EP disclosed
CN-1068333-A Has hydrazine analog derivative of pharmacologically active and preparation method thereof CIBA GEIGY AG (CH) 1993-01-27 CN disclosed
EP-0521827-A1 Pharmacological active hydrazin derivatives and process for their preparation CIBA-GEIGY AG (CH) 1993-01-07 EP disclosed
CN-1035283-A Process for producing tert-butyl 3-oxobutyrate and use thereof TAKEDA CHEMICAL INDUSTRIES LTD (JP) 1989-09-06 CN disclosed
EP-0329606-A2 Antibiotics from myxocuccos CIBA-GEIGY AG (CH) 1989-08-23 EP disclosed
EP-0173226-B1 PROCESS FOR THE PREPARATION OF BETA-FORMYL PROPIONIC ACID TERT.-BUTYL ESTER Ruhrchemie Aktiengesellschaft (DE) 1988-05-25 EP disclosed
EP-0173226-B1 PROCESS FOR THE PREPARATION OF BETA-FORMYL PROPIONIC ACID TERT.-BUTYL ESTER Ruhrchemie Aktiengesellschaft (DE) 1988-05-25 EP disclosed
EP-0173226-A1 Process for the preparation of beta-formyl propionic acid tert.-butyl ester Ruhrchemie Aktiengesellschaft (DE) 1986-03-05 EP disclosed
EP-0173226-A1 Process for the preparation of beta-formyl propionic acid tert.-butyl ester Ruhrchemie Aktiengesellschaft (DE) 1986-03-05 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250382264-A1 HETEROCYCLE-CONTAINING AMINO ACID COMPOUND AND COMPLEX NR2C2, NR3C2, NPR1 HDAC6 2365/4885HDAC1 261/4885HDAC2 413/4885
US-20230398225-A1 PD-L1/STING CONJUGATES AND METHODS OF USE STING1, PDCD1LG2, CD274 HDAC6 2529/4885HDAC1 3667/4885HDAC2 3806/4885
US-20140309192-A1 MODULATORS OF THE G PROTEIN-COUPLED MAS RECEPTOR AND THE TREATMENT OF DISORDERS RELATED THERETO MRGPRX1, MRGPRX2, AGTR1 HDAC6 1631/4885HDAC1 1757/4885HDAC2 2045/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.