Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | TSHR | P16473 | 2/20 | 0.43 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.43 |
| ▸ | GABRG2 | P18507 | 2/20 | 0.43 |
| ▸ | GABRB3 | P28472 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | FAAH | O00519 | 1/20 | 0.43 |
| ▸ | CA1 | P00915 | 1/20 | 0.43 |
| ▸ | CA2 | P00918 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.43 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.43 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.43 |
| ▸ | HTR2C | P28335 | 1/20 | 0.43 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.43 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.43 |
| ▸ | HTR2B | P41595 | 1/20 | 0.43 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30797325 | 1.00 | IRAK4 (0.44) | IRAK4HPGDTSHRGABRA1GABRG2 | |
| Hydrochloric Acid SCHEMBL30797245 | 0.98 | IRAK4 (0.43) | IRAK4HPGDTSHRGABRA1GABRG2 | |
| Hydrochloric Acid SCHEMBL29160773 | 0.98 | IRAK4 (0.43) | IRAK4HPGDTSHRGABRA1GABRG2 | |
| Oxalic Acid SCHEMBL23529511 | 0.95 | IRAK4 (0.41) | IRAK4HPGDTSHRGABRA1GABRG2 | |
| Maleic Acid SCHEMBL6137322 | 0.90 | KDM4E (0.44) | IRAK4HPGDTSHRGABRA1GABRG2 | |
| SCHEMBL2977145 | 0.88 | IRAK4 (0.50) | IRAK4HPGDTSHRKDM4EALDH1A1 | |
| SCHEMBL29214418 | 0.84 | GABRA1 (0.46) | HPGDTSHRGABRA1GABRG2GABRB3 | |
| SCHEMBL105262 | 0.84 | IRAK4 (0.55) | IRAK4HPGDTSHRGABRA1GABRG2 | |
| SCHEMBL31632660 | 0.84 | IRAK4 (0.55) | IRAK4HPGDTSHRGABRA1GABRG2 | |
| SCHEMBL16466774 | 0.82 | LMNA (0.45) | HPGDTSHRGABRA1GABRG2GABRB3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 331 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118359610-A | MENIN-MLL interaction inhibitors | 生命医药有限责任公司 | 2024-07-19 | — | — | CN | claimed |
| CN-117567232-A | Extraction separation method of alkyl benzothiophene in beta-methylnaphthalene | 中煤科工清洁能源股份有限公司 | 2024-02-20 | — | — | CN | claimed |
| CN-110139861-B | Pyran derivatives as CYP11A1 (cytochrome P450 monooxygenase 11A 1) inhibitors | 奥赖恩公司 | 2022-12-30 | — | — | CN | claimed |
| CN-109743875-B | Inhibitors of the MENIN-MLL interaction | 生命医药有限责任公司 | 2022-04-29 | — | — | CN | claimed |
| CN-113214552-B | Method for manufacturing rubber rain shoes with metallic color effect | 杭州星发彩印有限公司 | 2022-04-05 | — | — | CN | claimed |
| CN-113214552-A | Method for manufacturing rubber rain shoes with metallic color effect | 杭州星发彩印有限公司 | 2021-08-06 | — | — | CN | claimed |
| CN-111904962-A | Pharmaceutical composition containing PDE4 inhibitor and PI3 or dual PI 3-gamma kinase inhibitor | 理森制药股份公司 | 2020-11-10 | — | — | CN | claimed |
| CN-110325533-A | INHIBITORS OF THE MENIN-MLL INTERACTION | 生命医药有限责任公司 | 2019-10-11 | — | — | CN | claimed |
| CN-109743875-A | The inhibitor of MENIN-MLL interaction | 生命医药公司 | 2019-05-10 | — | — | CN | claimed |
| CN-104903300-B | COMT inhibitor | 霍夫曼-拉罗奇有限公司 | 2018-04-17 | — | — | CN | claimed |
| CN-101917845-A | Haloallylamine inhibitors of SSAO/VAP-1 and uses therefor | PHARMAXIS LTD | 2010-12-15 | — | — | CN | claimed |
| CN-1926113-A | Novel amido substituted hydroxy-6-phenylphenanthridines and their use as PDE4 inhibitors | ALTANA PHARMA AG (DE) | 2007-03-07 | — | — | CN | claimed |
| CN-1269805-C | 4- (phenyl-piperazinyl-methyl) -benzamide derivatives and their use for the treatment of pain, anxiety or gastrointestinal disorders | ASTRAZENECA AB (SE) | 2006-08-16 | — | — | CN | claimed |
| CN-1547579-A | 4-(phenyl-piperdin-4-ylidene-methyl)-benzamide derivatives and their use for the treatment of pain, anxiety or gastrointestinal disorders | — | 2004-11-17 | — | — | CN | claimed |
| CN-1527820-A | 4-(phenyl-piperazinyl-methyl)benzamide derivatives and their use for the treatment of pain, anxiety or gastrointestional disorders | — | 2004-09-08 | — | — | CN | claimed |
| CN-1527828-A | 4- (phenyl-piperidin-4-ylidene-methyl) -benzamide derivatives and their use for the treatment of pain, anxiety or gastrointestinal disorders | — | 2004-09-08 | — | — | CN | claimed |
| CN-1509271-A | 4- (phenyl-piperidin-4-ylidene-methyl) -benzamide derivatives and their use for the treatment of pain, anxiety or gastrointestinal disorders | — | 2004-06-30 | — | — | CN | claimed |
| EP-1395574-A1 | 4-(PHENYL-PIPERIDIN-4-YLIDENE-METHYL)-BENZAMIDE DERIVATIVES AND THEIR USE FOR THE TREATMENT OF PAIN, ANXIETY OR GASTROINTESTINAL DISORDERS | AstraZeneca AB (SE) | 2004-03-10 | — | — | EP | claimed |
| WO-2002094810-A1 | 4-(PHENYL-PIPERIDIN-4-YLIDENE-METHYL)-BENZAMIDE DERIVATIVES AND THEIR USE FOR THE TREATMENT OF PAIN, ANXIETY OR GASTROINTESTINAL DISORDERS | ASTRAZENECA AB (SE) | 2002-11-28 | — | — | WO | claimed |
| EP-0518819-B1 | Amidino compounds, their manufacture and use as medicament | CIBA GEIGY AG (CH) | 1995-08-02 | — | — | EP | claimed |