SCHEMBL4584279

SCHEMBL4584279

CC(C)(C)c1ccc(N(c2ccc(C(C)(C)C)cc2)c2cccc(B3OC(C)(C)C(C)(C)O3)c2)cc1

nearest known ligand 0.44

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
LIPG Q9Y5X9 14/20 0.44
LPL P06858 13/20 0.44
HIF1A Q16665 1/20 0.39
IRAK4 Q9NWZ3 1/20 0.32
MEN1 O00255 1/20 0.31
KMT2A Q03164 1/20 0.31
SMN1; SMN2 Q16637 1/20 0.31
FFAR1 O14842 1/20 0.30
EGFR P00533 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15553523 0.87 LIPG (0.49) LIPGLPLIRAK4MEN1KMT2A
SCHEMBL4585554 0.87 LPL (0.35) LIPGLPLHIF1A
SCHEMBL15583748 0.85 LPL (0.47) LIPGLPLHIF1A
SCHEMBL1702390 0.85 LIPG (0.50) LIPGLPLIRAK4
SCHEMBL14934699 0.85 LPL (0.47) LIPGLPLHIF1A
SCHEMBL23781315 0.85 LIPG (0.50) LIPGLPLIRAK4
SCHEMBL13636794 0.85 LIPG (0.39) LIPGLPLHIF1A
SCHEMBL24126360 0.84 HIF1A (0.38) LIPGLPLHIF1AFFAR1
SCHEMBL12000718 0.84 LIPG (0.47) LIPGLPLHIF1AIRAK4EGFR
SCHEMBL4585558 0.82 LPL (0.34) LIPGLPLHIF1A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7365198-B2 Silyl compound, light emitting material, and organic light emitting device using the same CANON KABUSHIKI KAISHA (JP) 2008-04-29 US disclosed
US-20070205715-A1 SILYL COMPOUND, LIGHT EMITTING MATERIAL, AND ORGANIC LIGHT EMITTING DEVICE USING THE SAME CANON KABUSHIKI KAISHA (JP) 2007-09-06 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070205715-A1 SILYL COMPOUND, LIGHT EMITTING MATERIAL, AND ORGANIC LIGHT EMITTING DEVICE USING THE SAME LAS1L, CCNL2, EML4 LIPG 2825/4885LPL 1558/4885HIF1A 3698/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.