SCHEMBL4585554

SCHEMBL4585554

CC(C)(C)c1ccc(N(c2cccc(B3OC(C)(C)C(C)(C)O3)c2)c2ccc3c(c2)C(C)(C)c2ccccc2-3)cc1

nearest known ligand 0.35

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
LPL P06858 3/20 0.35
LIPG Q9Y5X9 3/20 0.35
PDK2 Q15119 2/20 0.34
HIF1A Q16665 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13878215 0.91 LIPG (0.39) LPLLIPGPDK2
SCHEMBL24542909 0.91 LPL (0.38) LPLLIPGPDK2
SCHEMBL4585558 0.90 LPL (0.34) LPLLIPGHIF1A
SCHEMBL15845373 0.87 LIPG (0.46) LPLLIPGPDK2
SCHEMBL4584279 0.87 LIPG (0.44) LPLLIPGHIF1A
SCHEMBL15906970 0.86 LIPG (0.41) LPLLIPGPDK2
SCHEMBL15803118 0.84 LIPG (0.46) LPLLIPGPDK2
SCHEMBL31576189 0.84 LIPG (0.46) LPLLIPGPDK2
SCHEMBL15170052 0.84 LPL (0.44) LPLLIPGPDK2
SCHEMBL29557018 0.84 LPL (0.44) LPLLIPGPDK2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7365198-B2 Silyl compound, light emitting material, and organic light emitting device using the same CANON KABUSHIKI KAISHA (JP) 2008-04-29 US disclosed
US-20070205715-A1 SILYL COMPOUND, LIGHT EMITTING MATERIAL, AND ORGANIC LIGHT EMITTING DEVICE USING THE SAME CANON KABUSHIKI KAISHA (JP) 2007-09-06 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070205715-A1 SILYL COMPOUND, LIGHT EMITTING MATERIAL, AND ORGANIC LIGHT EMITTING DEVICE USING THE SAME LAS1L, CCNL2, EML4 LPL 1558/4885LIPG 2825/4885PDK2 3301/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.