Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | PGR | P06401 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | GFER | P55789 | 1/20 | 0.32 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.30 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.30 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.30 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.30 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.30 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.30 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.30 |
| ▸ | ESR1 | P03372 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4583841 | 0.77 | HSD11B1 (0.33) | KMT2AMEN1 | |
| SCHEMBL4584349 | 0.74 | ALDH1A1 (0.42) | KMT2AALDH1A1LMNAPGRMEN1 | |
| SCHEMBL3978462 | 0.74 | KMT2A (0.41) | KMT2AALDH1A1LMNAPGRMEN1 | |
| SCHEMBL29518424 | 0.70 | PGR (0.44) | KMT2AALDH1A1LMNAPGRMEN1 | |
| SCHEMBL31434421 | 0.70 | GRIN2D (0.39) | KMT2AALDH1A1LMNAPGRMEN1 | |
| SCHEMBL4583509 | 0.70 | KMT2A (0.41) | KMT2AALDH1A1LMNAPGRMEN1 | |
| SCHEMBL12339885 | 0.70 | ALDH1A1 (0.35) | KMT2AALDH1A1LMNAPGRMEN1 | |
| SCHEMBL3765963 | 0.69 | KMT2A (0.40) | KMT2AALDH1A1PGRMEN1POLB | |
| SCHEMBL4584297 | 0.67 | KMT2A (0.38) | KMT2AALDH1A1LMNAPGRMEN1 | |
| SCHEMBL5492318 | 0.67 | MEN1 (0.41) | KMT2AALDH1A1LMNAMEN1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7423180-B2 | Bis(3-amino-4-hydroxyphenyl)adamantane derivatives and process for production thereof | IDEMITSU KOSAN CO., LTD. (JP) | 2008-09-09 | — | — | US | disclosed |
| US-20060161016-A1 | Bis(3-amino-4-hydroxyphenyl)adamantane derivatives and process for production thereof | IDEMITSU KOSAN CO., LTD. (JP) | 2006-07-20 | — | — | US | disclosed |
| EP-1602641-A1 | BIS(3-AMINO-4-HYDROXYPHENYL)ADAMANTANE DERIVATIVES AND PROCESS FOR PRODUCTION THEREOF | IDEMITSU KOSAN COMPANY LIMITED (JP) | 2005-12-07 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060161016-A1 | Bis(3-amino-4-hydroxyphenyl)adamantane derivatives and process for production thereof | HTR3D, ALKBH3, ALKBH5 | KMT2A 1000/4885ALDH1A1 768/4885LMNA 1843/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.