Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.55 |
| ▸ | HTT | P42858 | 1/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.54 |
| ▸ | HPGD | P15428 | 2/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.54 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.52 |
| ▸ | RAB9A | P51151 | 3/20 | 0.52 |
| ▸ | NPC1 | O15118 | 2/20 | 0.52 |
| ▸ | AHR | P35869 | 1/20 | 0.52 |
| ▸ | RPS6KB1 | P23443 | 4/20 | 0.52 |
| ▸ | AURKA | O14965 | 3/20 | 0.52 |
| ▸ | SYK | P43405 | 7/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | PARP1 | P09874 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL22609596 | 0.98 | MAPT (0.54) | MAPTHTTALDH1A1HPGDKDM4E | |
| SCHEMBL28282980 | 0.94 | MAPK8 (0.52) | MAPTHTTALDH1A1HPGDKDM4E | |
| SCHEMBL2718370 | 0.94 | SYK (0.53) | MAPTHTTALDH1A1HPGDKDM4E | |
| SCHEMBL3718998 | 0.94 | MAPT (0.52) | MAPTHTTALDH1A1HPGDKDM4E | |
| SCHEMBL3638560 | 0.90 | MAPK1 (0.50) | MAPTHTTALDH1A1HPGDKDM4E | |
| SCHEMBL21774769 | 0.88 | SYK (0.48) | MAPTHTTALDH1A1HPGDKDM4E | |
| SCHEMBL21774760 | 0.88 | MAPT (0.45) | MAPTHTTALDH1A1HPGDKDM4E | |
| SCHEMBL21774801 | 0.87 | SYK (0.46) | MAPTHTTALDH1A1HPGDKDM4E | |
| SCHEMBL28284467 | 0.86 | BTK (0.49) | MAPTHTTALDH1A1HPGDKDM4E | |
| SCHEMBL21774807 | 0.86 | SYK (0.50) | MAPTHTTALDH1A1HPGDKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250270190-A1 | KIT INHIBITORS | BLUEPRINT MEDICINES CORPORATION | 2025-08-28 | — | — | US | disclosed |
| CN-110218211-A | A kind of simple and convenient process for preparing of nevirapine | 新发药业有限公司 | 2019-09-10 | — | — | CN | disclosed |
| CN-106061967-B | The nicotinamide compounds replaced through heteroaryl | 百时美施贵宝公司 | 2019-04-19 | — | — | CN | disclosed |
| US-9951020-B2 | Methods of making 2-halonicotinonitriles | VIRGINIA COMMONWEALTH UNIVERSITY (US) | 2018-04-24 | — | — | US | disclosed |
| US-9951020-B2 | Methods of making 2-halonicotinonitriles | VIRGINIA COMMONWEALTH UNIVERSITY (US) | 2018-04-24 | — | — | US | disclosed |
| US-20160221951-A1 | METHODS OF MAKING 2-HALONICOTINONITRILES | VIRGINIA COMMONWEALTH UNIVERSITY | 2016-08-04 | — | — | US | disclosed |
| US-20160221951-A1 | METHODS OF MAKING 2-HALONICOTINONITRILES | VIRGINIA COMMONWEALTH UNIVERSITY | 2016-08-04 | — | — | US | disclosed |
| WO-2015031718-A1 | METHODS OF MAKING 2-HALONICOTINONITRILES | MCQUADE D TYLER (US) | 2015-03-05 | — | — | WO | disclosed |
| WO-2008103899-A1 | PREPARATION AND UTILITY OF NON-NUCLEOSIDE REVERSE TRANSCRIPTASE INHIBITORS | AUSPEX PHARMACEUTICALS, INC. (US) | 2008-08-28 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250270190-A1 | KIT INHIBITORS | KIT, ABL1, APC | MAPT 4237/4885HTT 2531/4885ALDH1A1 1119/4885 |
| US-20160221951-A1 | METHODS OF MAKING 2-HALONICOTINONITRILES | NISCH, HCN2, HCN1 | MAPT 2653/4885HTT 244/4885ALDH1A1 647/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.