SCHEMBL4585188

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL18745247	0.98	ALDH1A1 (0.45)	RAB9AHPGDKMT2ANPC1MEN1
	SCHEMBL496557	0.83	ALDH1A1 (0.44)	KMT2AMEN1ALDH1A1MAPTL3MBTL1
	SCHEMBL13515147	0.83	ALDH1A1 (0.46)	RAB9AHPGDKMT2ANPC1MEN1
	SCHEMBL10493428	0.83	ALDH1A1 (0.46)	RAB9AHPGDKMT2ANPC1MEN1
	Water SCHEMBL19100116	0.81	ALDH1A1 (0.43)	KMT2AALDH1A1MAPTL3MBTL1CYP1A2
	Phosphine SCHEMBL28070707	0.81	ALDH1A1 (0.43)	KMT2AMEN1ALDH1A1MAPTL3MBTL1
	SCHEMBL4585873	0.81	ALDH1A1 (0.40)	RAB9AHPGDKMT2ANPC1MEN1
	SCHEMBL4587291	0.80	RAB9A (0.39)	RAB9AHPGDKMT2ANPC1MEN1
	SCHEMBL4585844	0.80	RAB9A (0.39)	RAB9AHPGDKMT2ANPC1MEN1
	SCHEMBL15239491	0.79	RAB9A (0.38)	RAB9AHPGDKMT2ANPC1MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.