SCHEMBL4585392

SCHEMBL4585392

Fc1ccc(-c2cc(-c3ccc(F)cc3)c3ccc4c(-c5ccc(F)cc5)cc(-c5ccc(F)cc5)c5ccc2c3c54)cc1

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GRM2 Q14416 4/20 0.43
NR4A2 P43354 1/20 0.39
NPC1 O15118 2/20 0.39
RAB9A P51151 2/20 0.39
SMN1; SMN2 Q16637 2/20 0.39
KDM4E B2RXH2 1/20 0.39
ALDH1A1 P00352 1/20 0.39
GAA P10253 1/20 0.39
HPGD P15428 1/20 0.39
PPARG P37231 1/20 0.39
PPARD Q03181 1/20 0.39
PPARA Q07869 1/20 0.39
HSD17B10 Q99714 1/20 0.39
PTGS2 P35354 5/20 0.38
PTGS1 P23219 2/20 0.38
MAOB P27338 1/20 0.37
TDO2 P48775 1/20 0.36
CDC25A P30304 1/20 0.36
CDC25C P30307 1/20 0.36
TNKS2 Q9H2K2 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15945804 0.91 GRM2 (0.46) GRM2NR4A2HPGDPTGS2PTGS1
SCHEMBL13251076 0.91 GRM2 (0.46) GRM2NR4A2HPGDPTGS2PTGS1
SCHEMBL13250966 0.91 GRM2 (0.46) GRM2NR4A2HPGDPTGS2PTGS1
SCHEMBL13250975 0.89 ACHE (0.52) GRM2NPC1RAB9ASMN1; SMN2KDM4E
SCHEMBL13251091 0.89 ACHE (0.52) GRM2NPC1RAB9ASMN1; SMN2KDM4E
SCHEMBL13251081 0.89 GRM2 (0.45) GRM2NR4A2HPGDPTGS1GCGR
SCHEMBL13250969 0.89 GRM2 (0.45) GRM2NR4A2HPGDPTGS1GCGR
SCHEMBL14308862 0.88 GRM2 (0.37) GRM2NR4A2NPC1RAB9ASMN1; SMN2
SCHEMBL14923417 0.88 TNKS2 (0.44) GRM2NPC1RAB9ASMN1; SMN2KDM4E
SCHEMBL13251097 0.86 GRM2 (0.41) GRM2NPC1RAB9ASMN1; SMN2KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11177450-B2 Organoelectroluminescent element, and light emission device, display device, and illumination device in which said organoelectroluminescent element is used UDC IRELAND LIMITED (IE) 2021-11-16 US disclosed
US-9287507-B2 Organic electroluminescent element, compounds and materials used for the organic electroluminescent element, and light-emitting, display and illuminating devices using the elements UDC Ireland (IE) 2016-03-15 US disclosed
US-8940409-B2 Organic light emitting material and organic light emitting device using the same LG DISPLAY CO., LTD. (KR) 2015-01-27 US disclosed
US-8940409-B2 Organic light emitting material and organic light emitting device using the same LG DISPLAY CO., LTD. (KR) 2015-01-27 US disclosed
US-20140225085-A1 Organoelectroluminescent Element, and Light Emission Device, Display Device, and Illumination Device in which Said Organoelectroluminescent Element is Used UDC IRELAND LIMITED (IE) 2014-08-14 US disclosed
US-20140225085-A1 Organoelectroluminescent Element, and Light Emission Device, Display Device, and Illumination Device in which Said Organoelectroluminescent Element is Used UDC IRELAND LIMITED (IE) 2014-08-14 US disclosed
US-20130214259-A1 ORGANIC ELECTROLUMINESCENT ELEMENT, COMPOUNDS AND MATERIALS USED FOR THE ORGANIC ELECTROLUMINESCENT ELEMENT, AND LIGHT-EMITTING, DISPLAY AND ILLUMINATING DEVICES USING THE ELEMENTS UDC IRELAND LIMITED (IE) 2013-08-22 US disclosed
US-20130214259-A1 ORGANIC ELECTROLUMINESCENT ELEMENT, COMPOUNDS AND MATERIALS USED FOR THE ORGANIC ELECTROLUMINESCENT ELEMENT, AND LIGHT-EMITTING, DISPLAY AND ILLUMINATING DEVICES USING THE ELEMENTS UDC IRELAND LIMITED (IE) 2013-08-22 US disclosed
US-20100164374-A1 Organic light emitting material and organic light emitting device using the same LG DISPLAY CO., LTD. (KR) 2010-07-01 US disclosed
US-20100164374-A1 Organic light emitting material and organic light emitting device using the same LG DISPLAY CO., LTD. (KR) 2010-07-01 US disclosed
US-20080105865-A1 Pyrene Based Compound and Light Emitting Transistor Element Using the Same PIONEER CORPORATION (JP) 2008-05-08 US disclosed
US-20080105865-A1 Pyrene Based Compound and Light Emitting Transistor Element Using the Same PIONEER CORPORATION (JP) 2008-05-08 US disclosed
US-20080105865-A1 Pyrene Based Compound and Light Emitting Transistor Element Using the Same PIONEER CORPORATION (JP) 2008-05-08 US disclosed
EP-1816114-A1 PYRENE COMPOUND AND LIGHT EMITTING TRANSISTOR DEVICE UTILIZING THE SAME Rohm Co., Ltd. (JP) 2007-08-08 EP disclosed
EP-1816114-A1 PYRENE COMPOUND AND LIGHT EMITTING TRANSISTOR DEVICE UTILIZING THE SAME Rohm Co., Ltd. (JP) 2007-08-08 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080105865-A1 Pyrene Based Compound and Light Emitting Transistor Element Using the Same CYP1A1, SULT1A1, SULT1E1 GRM2 3323/4885NR4A2 398/4885NPC1 715/4885
US-20100164374-A1 Organic light emitting material and organic light emitting device using the same CRY1, L3MBTL4, TMSB4X GRM2 1527/4885NR4A2 403/4885NPC1 1790/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.