Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 13/20 | 0.47 |
| ▸ | SLC6A4 | P31645 | 10/20 | 0.47 |
| ▸ | SNCA | P37840 | 2/20 | 0.40 |
| ▸ | YTHDC1 | Q96MU7 | 1/20 | 0.40 |
| ▸ | SLC6A3 | Q01959 | 8/20 | 0.39 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.39 |
| ▸ | HTR6 | P50406 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4585074 | 0.82 | SLC6A2 (0.52) | SLC6A2SLC6A4YTHDC1SLC6A3PDK1 | |
| SCHEMBL2877349 | 0.76 | SLC6A2 (0.73) | SLC6A2SLC6A4YTHDC1SLC6A3 | |
| SCHEMBL1427866 | 0.74 | ALDH1A1 (0.48) | SLC6A2SLC6A4SNCASLC6A3 | |
| SCHEMBL27570737 | 0.72 | ALOX5 (0.53) | SNCA | |
| Hydrochloric Acid SCHEMBL15012233 | 0.70 | SLC6A2 (0.57) | SLC6A2SLC6A4SLC6A3 | |
| Hydrochloric Acid SCHEMBL15012232 | 0.70 | SLC6A2 (0.57) | SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL6307462 | 0.69 | SLC6A2 (0.56) | SLC6A2SLC6A4YTHDC1SLC6A3 | |
| SCHEMBL5673194 | 0.68 | SLC6A2 (0.51) | SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL5428676 | 0.68 | SLC6A2 (0.70) | SLC6A2SLC6A4SLC6A3 | |
| Hydrochloric Acid SCHEMBL6307333 | 0.68 | SLC6A2 (0.54) | SLC6A2SLC6A4YTHDC1SLC6A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1689493-A4 | CALCITONIN GENE RELATED PEPTIDE RECEPTOR ANTAGONISTS | BRISTOL MYERS SQUIBB CO (US) | 2008-04-23 | — | — | EP | disclosed |
| EP-1689493-A1 | CALCITONIN GENE RELATED PEPTIDE RECEPTOR ANTAGONISTS | Bristol-Myers Squibb Pharma Company (US) | 2006-08-16 | — | — | EP | disclosed |
| WO-2005065779-A1 | CALCITONIN GENE RELATED PEPTIDE RECEPTOR ANTAGONISTS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2005-07-21 | — | — | WO | disclosed |