Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.53 |
| ▸ | RECQL | P46063 | 1/20 | 0.53 |
| ▸ | PTGS1 | P23219 | 3/20 | 0.43 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.43 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.43 |
| ▸ | CA2 | P00918 | 2/20 | 0.42 |
| ▸ | CA1 | P00915 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.42 |
| ▸ | GAA | P10253 | 4/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | TYR | P14679 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | GLRA3 | O75311 | 1/20 | 0.41 |
| ▸ | GLRB | P48167 | 1/20 | 0.41 |
| ▸ | TNFRSF1A | P19438 | 1/20 | 0.40 |
| ▸ | EGFR | P00533 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL47590 | 0.88 | LMNA (0.55) | LMNARECQLPTGS1PTGS2ALOX5 | |
| SCHEMBL10082434 | 0.85 | LMNA (0.37) | LMNARECQLPTGS1PTGS2ALOX5 | |
| SCHEMBL7792941 | 0.85 | LMNA (0.54) | LMNARECQLPTGS1PTGS2ALOX5 | |
| SCHEMBL8960347 | 0.81 | LMNA (0.50) | LMNARECQLPTGS1PTGS2ALOX5 | |
| SCHEMBL9446389 | 0.79 | LMNA (0.46) | LMNARECQLPTGS1PTGS2ALOX5 | |
| SCHEMBL8339389 | 0.79 | CA2 (0.48) | LMNARECQLPTGS1PTGS2CA2 | |
| SCHEMBL8335067 | 0.78 | KDM4E (0.52) | LMNARECQLPTGS1PTGS2ALOX5 | |
| SCHEMBL30924511 | 0.77 | CYP1A2 (0.55) | LMNARECQLPTGS1PTGS2ALOX5 | |
| SCHEMBL14532115 | 0.77 | LMNA (0.45) | LMNARECQLPTGS1PTGS2ALOX5 | |
| SCHEMBL17500097 | 0.77 | CA2 (0.50) | LMNARECQLCA2CA1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8067402-B2 | Methods and systems for coating an oral surface | ALLACCEM, INC. (US) | 2011-11-29 | — | — | US | disclosed |
| US-20070202342-A1 | Applying to an oral surface (teeth or gums)one or more bridged polycyclic compounds comprising at least two cyclic groups defined in part by quaternary ammonium moieties; microbiocides; self-cleaning; dentistry; bonding agents, resin cements, sealants | ALLACCEM, INC. | 2007-08-30 | — | — | US | disclosed |