Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | CCR5 | P51681 | 2/20 | 0.39 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.38 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.37 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.36 |
| ▸ | SLC6A4 | P31645 | 5/20 | 0.36 |
| ▸ | SLC6A2 | P23975 | 4/20 | 0.36 |
| ▸ | SLC6A3 | Q01959 | 3/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | GAA | P10253 | 2/20 | 0.36 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | CACNA1B | Q00975 | 2/20 | 0.36 |
| ▸ | MBTPS1 | Q14703 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18361366 | 0.82 | MEN1 (0.44) | MAPTOPRD1LOXL2SLC6A4KCNH2 | |
| Hydrochloric Acid SCHEMBL21043567 | 0.81 | MEN1 (0.44) | MAPTOPRD1LOXL2SLC6A4KCNH2 | |
| SCHEMBL18361056 | 0.80 | MEN1 (0.41) | MAPTOPRD1LOXL2SLC6A4SLC6A2 | |
| Hydrochloric Acid SCHEMBL21043585 | 0.79 | MEN1 (0.41) | MAPTOPRD1LOXL2SLC6A4SLC6A2 | |
| SCHEMBL4585642 | 0.77 | LOXL2 (0.39) | MAPTEPHX1OPRD1LOXL2SLC6A4 | |
| SCHEMBL4247136 | 0.77 | CCR5 (0.51) | MAPTCCR5OPRD1SLC6A4SLC6A2 | |
| SCHEMBL4585576 | 0.75 | HTR1F (0.36) | GAACACNA1B | |
| SCHEMBL18361035 | 0.75 | NOTUM (0.46) | MAPTOPRD1KDM4EALDH1A1GAA | |
| SCHEMBL28363673 | 0.73 | NOTUM (0.43) | SLC6A4SLC6A2SLC6A3KCNH2KDM4E | |
| SCHEMBL4587113 | 0.71 | CCR5 (0.57) | CCR5OPRD1CACNA1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1708703-A4 | CHEMOKINE RECEPTOR BINDING COMPOUNDS | ANORMED INC (CA) | 2008-04-09 | — | — | EP | disclosed |
| EP-1708703-A2 | CHEMOKINE RECEPTOR BINDING COMPOUNDS | ANORMED INC. (CA) | 2006-10-11 | — | — | EP | disclosed |
| WO-2005059107-A2 | CHEMOKINE RECEPTOR BINDING COMPOUNDS | ANORMED INC. (CA) | 2005-06-30 | — | — | WO | disclosed |