Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | MAOB | P27338 | 1/20 | 0.37 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 5/20 | 0.35 |
| ▸ | RAB9A | P51151 | 5/20 | 0.35 |
| ▸ | TSHR | P16473 | 3/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.35 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.35 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.35 |
| ▸ | RELA | Q04206 | 1/20 | 0.35 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.33 |
| ▸ | TNKS | O95271 | 1/20 | 0.33 |
| ▸ | PTPRC | P08575 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 3/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL769634 | 0.81 | ALDH1A1 (0.45) | ALDH1A1MAPK1TDP1CYP2A6SMN1; SMN2 | |
| SCHEMBL25097 | 0.81 | ALDH1A1 (0.45) | ALDH1A1MAPK1TDP1CYP2A6SMN1; SMN2 | |
| SCHEMBL769959 | 0.81 | ALDH1A1 (0.45) | ALDH1A1MAPK1TDP1CYP2A6SMN1; SMN2 | |
| SCHEMBL27574065 | 0.81 | MAOA (0.40) | ALDH1A1MAPK1MAOBNPC1RAB9A | |
| SCHEMBL38202 | 0.80 | ALDH1A1 (0.42) | ALDH1A1MAPK1TDP1CYP2A6NPC1 | |
| SCHEMBL183516 | 0.80 | ALDH1A1 (0.35) | ALDH1A1RAB9A | |
| SCHEMBL41140 | 0.80 | ALDH1A1 (0.42) | ALDH1A1MAPK1TDP1CYP2A6NPC1 | |
| SCHEMBL17046416 | 0.80 | ALDH1A1 (0.31) | ALDH1A1MAPK1TDP1MAOB | |
| SCHEMBL1411316 | 0.77 | MMP3 (0.48) | ALDH1A1TDP1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL6607460 | 0.77 | CYP3A4 (0.48) | ALDH1A1TDP1MAOBNPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 31 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108264485-B | One kind being based on bipolar host material, synthetic method and the application of spiral shell [fluorenes -9,2 '-imidazoles] | 广东阿格蕾雅光电材料有限公司 | 2019-07-23 | — | — | CN | disclosed |
| CN-108269925-B | The organic electroluminescence device of bipolar material of main part containing spiral shell [fluorenes -9,2 '-imidazoles] group | 广东阿格蕾雅光电材料有限公司 | 2019-07-23 | — | — | CN | disclosed |
| CN-109791984-A | Material for photoelectric conversion element for imaging element and photoelectric conversion element containing same | 日本化药株式会社 | 2019-05-21 | — | — | CN | disclosed |
| CN-108269925-A | The organic electroluminescence device of bipolar material of main part containing spiral shell [fluorenes -9,2 '-imidazoles] group | 广东阿格蕾雅光电材料有限公司 | 2018-07-10 | — | — | CN | disclosed |
| CN-108264485-A | One kind is based on bipolar host material, synthetic method and the application of spiral shell [fluorenes -9,2 '-imidazoles] | 广东阿格蕾雅光电材料有限公司 | 2018-07-10 | — | — | CN | disclosed |
| CN-107108494-A | The electronic installation of organic compound and the organic layer for including organic compound | 陶氏环球技术有限责任公司 | 2017-08-29 | — | — | CN | disclosed |
| CN-103709180-B | Containing the condensed-nuclei aromatics derivant of imidazo [1,2-a] pyridine groups and the application in OLED thereof | 昆山维信诺显示技术有限公司 | 2016-12-21 | — | — | CN | disclosed |
| EP-1556364-A4 | ISOTHIAZOLE DERIVATIVES, PROCESS FOR THE PREPARATION THEREOF, AND PHARMACEUTICAL COMPOSITION INCLUDING THE SAME | CJ CORP (KR) | 2008-04-16 | — | — | EP | disclosed |
| EP-1813152-A1 | Fungicidal mixture based on 3,4-disubstituted biphenylanilides | BASF AKTIENGESELLSCHAFT (DE) | 2007-08-01 | — | — | EP | disclosed |
| EP-1670757-A1 | PYRROLE AND PYRAZOLE DERIVATIVES AS POTENTIATORS OF GLUTAMATE RECEPTORS | ELI LILLY AND COMPANY (US) | 2006-06-21 | — | — | EP | disclosed |
| WO-2001019829-A2 | PYRAZOLOPYRIMIDINES AS THERAPEUTIC AGENTS | BASF AKTIENGESELLSCHAFT (DE) | 2001-03-22 | — | — | WO | disclosed |
| US-6030975-A | ANTAGONIST OF ENDOTHELINS, I.E. INHIBITION OF BINDING WITH RECEPTOR; ANTITUMOR AND -CARCINOGENIC AGENTS; SIDE EFFECT REDUCTION | BASF AKTIENGESELLSCHAFT (DE) | 2000-02-29 | — | — | US | disclosed |
| US-5932730-A | Carboxylic acid derivatives, their preparation and use | BASF AKTIENGESELLSCHAFT (DE) | 1999-08-03 | — | — | US | disclosed |
| US-5190958-A | Fungicides | SHELL RESEARCH LIMITED (GB) | 1993-03-02 | — | — | US | disclosed |
| US-4808607-A | ATHEROSCLEROSIS, HYPERLIPOPROTEINEMIA | SANDOZ PHARM. CORP. (US) | 1989-02-28 | — | — | US | disclosed |
| US-4755606-A | Imidazolyl-3,5-di-(diphenyl-butylsilyloxy) carboxylic acid ester intermediates | SANDOZ PHARM. CORP. (US) | 1988-07-05 | — | — | US | disclosed |
| US-4530922-A | Fungicidal imidazoles and triazoles containing silicon | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1985-07-23 | — | — | US | disclosed |
| US-4455421-A | ANTIFERTILITY, ANTIULCER AGENTS; TETRAZOLE DERIVATIVES | PFIZER INC. (US) | 1984-06-19 | — | — | US | disclosed |
| US-4365077-A | ANTIFERTILITY, ANTIULCER | PFIZER INC. (US) | 1982-12-21 | — | — | US | disclosed |
| US-4157341-A | 11-Desoxy-16-aryloxy-ω-tetranorprostaglandins | PFIZER INC. (US) | 1979-06-05 | — | — | US | disclosed |