Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NFE2L2 | Q16236 | 5/20 | 0.54 |
| ▸ | TRPA1 | O75762 | 2/20 | 0.54 |
| ▸ | MAOB | P27338 | 2/20 | 0.44 |
| ▸ | RELA | Q04206 | 1/20 | 0.43 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.43 |
| ▸ | MAOA | P21397 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | CHAT | P28329 | 2/20 | 0.40 |
| ▸ | DPYD | Q12882 | 1/20 | 0.39 |
| ▸ | APP | P05067 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6405637 | 0.90 | NFE2L2 (0.48) | NFE2L2TRPA1MAOBRELACYP19A1 | |
| SCHEMBL6031700 | 0.90 | NFE2L2 (0.48) | NFE2L2TRPA1MAOBRELACYP19A1 | |
| SCHEMBL1861624 | 0.90 | NFE2L2 (0.48) | NFE2L2TRPA1MAOBRELACYP19A1 | |
| SCHEMBL14196540 | 0.89 | NFE2L2 (0.44) | NFE2L2TRPA1MAOBRELACYP19A1 | |
| SCHEMBL22711285 | 0.86 | RELA (0.50) | NFE2L2TRPA1MAOBRELACYP19A1 | |
| SCHEMBL21647821 | 0.86 | RELA (0.50) | NFE2L2TRPA1MAOBRELACYP19A1 | |
| SCHEMBL27661663 | 0.86 | RELA (0.50) | NFE2L2TRPA1MAOBRELACYP19A1 | |
| SCHEMBL3201261 | 0.84 | CYP2A6 (0.43) | NFE2L2TRPA1MEN1KMT2AAPP | |
| SCHEMBL14196537 | 0.83 | NFE2L2 (0.43) | NFE2L2TRPA1MAOBRELACYP19A1 | |
| SCHEMBL14196554 | 0.83 | NFE2L2 (0.43) | NFE2L2TRPA1MAOBRELACYP19A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1957605-B1 | ORGANIC ELECTROLUMINESCENT DEVICES | MERCK PATENT GMBH (DE) | 2017-01-11 | — | — | EP | disclosed |
| EP-1957603-B1 | ORGANIC ELECTROLUMINESCENT DEVICES | MERCK PATENT GMBH (DE) | 2015-10-14 | — | — | EP | disclosed |
| US-8785001-B2 | Organic electroluminescent devices | MERCK PATENT GMBH (DE) | 2014-07-22 | — | — | US | disclosed |
| US-8304095-B2 | Organic electroluminescent devices | MERCK PATENT GMBH (DE) | 2012-11-06 | — | — | US | disclosed |
| US-20080297037-A1 | Organic Electroluminescent Devices | MERCK PATENT GMBH (DE) | 2008-12-04 | — | — | US | disclosed |
| US-20080272693-A1 | Organic Electroluminescent Devices | MERCK PATENT GMBH (DE) | 2008-11-06 | — | — | US | disclosed |
| EP-1957605-A1 | ORGANIC ELECTROLUMINESCENT DEVICES | Merck Patent GmbH (DE) | 2008-08-20 | — | — | EP | disclosed |
| EP-1957603-A1 | ORGANIC ELECTROLUMINESCENT DEVICES | Merck Patent GmbH (DE) | 2008-08-20 | — | — | EP | disclosed |
| WO-2007065549-A1 | ORGANIC ELECTROLUMINESCENT DEVICES | MERCK PATENT GMBH (DE) | 2007-06-14 | — | — | WO | disclosed |
| WO-2007065547-A1 | ORGANIC ELECTROLUMINESCENT DEVICES | MERCK PATENT GMBH (DE) | 2007-06-14 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080272693-A1 | Organic Electroluminescent Devices | EML4, MT-ND4L, EPCAM | NFE2L2 423/4885TRPA1 342/4885MAOB 344/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.