Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
| ▸ | CASP7 | P55210 | 1/20 | 0.32 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | PDE3B | Q13370 | 2/20 | 0.31 |
| ▸ | PDE3A | Q14432 | 2/20 | 0.31 |
| ▸ | NQO2 | P16083 | 1/20 | 0.30 |
| ▸ | APEX1 | P27695 | 1/20 | 0.30 |
| ▸ | LDHA | P00338 | 1/20 | 0.30 |
| ▸ | LDHB | P07195 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12415320 | 0.76 | ACHE (0.39) | MAPK1ALDH1A1 | |
| SCHEMBL1134728 | 0.76 | TSHR (0.41) | TSHRCYP3A4MAPK1ALDH1A1CYP1A2 | |
| SCHEMBL12589323 | 0.73 | TSHR (0.36) | TSHRCYP3A4MAPK1ALDH1A1 | |
| SCHEMBL1135594 | 0.69 | TSHR (0.44) | TSHRCYP3A4MAPK1ALDH1A1NQO2 | |
| SCHEMBL29637482 | 0.69 | TSHR (0.44) | TSHRCYP3A4MAPK1ALDH1A1NQO2 | |
| SCHEMBL28600360 | 0.69 | APEX1 (0.41) | TSHRCYP3A4APEX1 | |
| SCHEMBL28563878 | 0.69 | CYP1A2 (0.41) | CYP3A4MAPK1ALDH1A1CYP1A2ALOX15 | |
| SCHEMBL31606803 | 0.69 | ESR1 (0.43) | TSHRCYP3A4MAPK1ALDH1A1 | |
| SCHEMBL11525099 | 0.67 | APEX1 (0.33) | TSHRALDH1A1CYP1A2APEX1 | |
| SCHEMBL25704920 | 0.67 | ESR1 (0.42) | TSHRCYP3A4MAPK1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7365198-B2 | Silyl compound, light emitting material, and organic light emitting device using the same | CANON KABUSHIKI KAISHA (JP) | 2008-04-29 | — | — | US | disclosed |
| US-20070205715-A1 | SILYL COMPOUND, LIGHT EMITTING MATERIAL, AND ORGANIC LIGHT EMITTING DEVICE USING THE SAME | CANON KABUSHIKI KAISHA (JP) | 2007-09-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070205715-A1 | SILYL COMPOUND, LIGHT EMITTING MATERIAL, AND ORGANIC LIGHT EMITTING DEVICE USING THE SAME | LAS1L, CCNL2, EML4 | TSHR 4768/4885CYP3A4 105/4885MAPK1 2850/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.