Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.35 |
| ▸ | CYP2A6 | P11509 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.35 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.35 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.35 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.35 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.35 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.35 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.35 |
| ▸ | LDHA | P00338 | 2/20 | 0.35 |
| ▸ | LDHB | P07195 | 2/20 | 0.35 |
| ▸ | NQO2 | P16083 | 1/20 | 0.33 |
| ▸ | NOS3 | P29474 | 1/20 | 0.33 |
| ▸ | NOS1 | P29475 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24795052 | 0.82 | CYP3A4 (0.53) | TSHRCYP3A4MAPK1ALDH1A1CYP1A2 | |
| SCHEMBL12589323 | 0.79 | TSHR (0.36) | TSHRCYP3A4MAPK1ALDH1A1 | |
| SCHEMBL601246 | 0.79 | CYP1A2 (0.53) | TSHRCYP3A4MAPK1ALDH1A1CYP1A2 | |
| SCHEMBL30674801 | 0.79 | CYP1A2 (0.53) | TSHRCYP3A4MAPK1ALDH1A1CYP1A2 | |
| SCHEMBL8109982 | 0.78 | TSHR (0.57) | TSHRCYP3A4MAPK1ALDH1A1CYP1A2 | |
| SCHEMBL39444 | 0.78 | TSHR (0.57) | TSHRCYP3A4MAPK1ALDH1A1CYP1A2 | |
| SCHEMBL8840937 | 0.77 | CYP1A2 (0.46) | CYP3A4ALDH1A1CYP1A2CYP2A6KDM4E | |
| SCHEMBL4586367 | 0.76 | TSHR (0.40) | TSHRCYP3A4MAPK1ALDH1A1CYP1A2 | |
| SCHEMBL3873017 | 0.74 | MAPT (0.47) | KDM4ENQO2ACHEMAPTNPC1 | |
| SCHEMBL5180999 | 0.74 | TSHR (0.53) | TSHRCYP3A4MAPK1ALDH1A1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2285340-B1 | INITIATOR SYSTEM WITH BIPHENYLENE DERIVATES, METHOD OF PRODUCTION AND USE THEREOF | 3M INNOVATIVE PROPERTIES CO (US) | 2013-07-31 | — | — | EP | disclosed |
| US-8436067-B2 | Initiator system with biphenylene derivates, method of production and use thereof | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2013-05-07 | — | — | US | disclosed |
| US-20110124764-A1 | INITIATOR SYSTEM WITH BIPHENYLENE DERIVATES, METHOD OF PRODUCTION AND USE THEREOF | 3M INNOVATIVE PROPERTIES COMPANY | 2011-05-26 | — | — | US | disclosed |
| EP-2285340-A2 | INITIATOR SYSTEM WITH BIPHENYLENE DERIVATES, METHOD OF PRODUCTION AND USE THEREOF | 3M Innovative Properties Company (US) | 2011-02-23 | — | — | EP | disclosed |
| WO-2009152211-A2 | INITIATOR SYSTEM WITH BIPHENYLENE DERIVATES, METHOD OF PRODUCTION AND USE THEREOF | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2009-12-17 | — | — | WO | disclosed |
| EP-2133063-A1 | Initiator system with biphenylene derivates, method of production and use thereof | 3M Innovative Properties Company (US) | 2009-12-16 | — | — | EP | disclosed |
| US-7585928-B2 | monomers of acetylenic homo- or copolymers; cured polymers has low dielectric constant as insulating layers in microelectronic devices | DOW GLOBAL TECHNOLOGIES (US) | 2009-09-08 | — | — | US | disclosed |
| US-20070027278-A1 | Multifunctional monomers containing bound mesogenic poragen forming moieties and polyarylene compositions therefrom | DOW GLOBAL TECHNOLOGIES LLC | 2007-02-01 | — | — | US | disclosed |
| WO-2005042613-A1 | MULTIFUNCTIONAL MONOMERS CONTAINING BOUND MESOGENIC PORAGEN FORMING MOIETIES AND POLYARYLENE COMPOSITIONS THEREFROM | DOW GLOBAL TECHNOLOGIES INC. (US) | 2005-05-12 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110124764-A1 | INITIATOR SYSTEM WITH BIPHENYLENE DERIVATES, METHOD OF PRODUCTION AND USE THEREOF | AIPL1, BMI1, MLLT1 | TSHR 3640/4885CYP3A4 227/4885MAPK1 2634/4885 |
| US-20070027278-A1 | Multifunctional monomers containing bound mesogenic poragen forming moieties and polyarylene compositions therefrom | LRBA, CD74, BMP2 | TSHR 4859/4885CYP3A4 783/4885MAPK1 4595/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.