Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 2/20 | 0.60 |
| ▸ | ITGA2B | P08514 | 2/20 | 0.60 |
| ▸ | SLC7A5 | Q01650 | 4/20 | 0.58 |
| ▸ | PCNA | P12004 | 1/20 | 0.47 |
| ▸ | LNPEP | Q9UIQ6 | 2/20 | 0.47 |
| ▸ | ERAP2 | Q6P179 | 1/20 | 0.46 |
| ▸ | GSR | P00390 | 1/20 | 0.45 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.45 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.43 |
| ▸ | ALPI | P09923 | 1/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | XIAP | P98170 | 1/20 | 0.43 |
| ▸ | LTA4H | P09960 | 1/20 | 0.43 |
| ▸ | THRB | P10828 | 1/20 | 0.42 |
| ▸ | MMP2 | P08253 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | USP2 | O75604 | 1/20 | 0.42 |
| ▸ | EGFR | P00533 | 1/20 | 0.42 |
| ▸ | LCK | P06239 | 1/20 | 0.42 |
| ▸ | FYN | P06241 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL571283 | 0.95 | ITGB3 (0.65) | ITGB3ITGA2BSLC7A5LNPEPGSR | |
| Cysteine SCHEMBL9755060 | 0.89 | ITGB3 (0.58) | ITGB3ITGA2BSLC7A5LNPEPGSR | |
| Glutamic Acid SCHEMBL1696963 | 0.88 | ITGB3 (0.57) | ITGB3ITGA2BSLC7A5LNPEPGSR | |
| Leucine SCHEMBL4586599 | 0.87 | ITGB3 (0.56) | ITGB3ITGA2BSLC7A5LNPEPERAP2 | |
| Tyrosine SCHEMBL3303402 | 0.87 | SLC7A5 (0.73) | ITGB3ITGA2BSLC7A5PCNALNPEP | |
| SCHEMBL60228 | 0.87 | SLC7A5 (0.73) | ITGB3ITGA2BSLC7A5PCNAPTPN1 | |
| SCHEMBL11676390 | 0.87 | SLC7A5 (0.73) | ITGB3ITGA2BSLC7A5PCNAPTPN1 | |
| SCHEMBL10978818 | 0.87 | SLC7A5 (0.73) | ITGB3ITGA2BSLC7A5PCNAPTPN1 | |
| Tyrosine SCHEMBL21925058 | 0.87 | SLC7A5 (0.73) | ITGB3ITGA2BSLC7A5PCNALNPEP | |
| SCHEMBL11370023 | 0.87 | SLC7A5 (0.73) | ITGB3ITGA2BSLC7A5PCNAPTPN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116063253-B | Biodegradable epoxy cross-linking agent and preparation method and application thereof | 长春圣博玛生物材料有限公司 | 2023-07-21 | — | — | CN | disclosed |
| CN-116063253-A | Biodegradable epoxy cross-linking agent and preparation method and application thereof | 长春圣博玛生物材料有限公司 | 2023-05-05 | — | — | CN | disclosed |
| EP-1740601-B1 | MYOSIN LIGHT CHAIN KINASE INHIBITORS AND THEIR USE | UNIV CHICAGO (US) | 2012-12-05 | — | — | EP | disclosed |
| US-20100016242-A1 | MYOSIN LIGHT CHAIN KINASE INHIBITORS AND METHODS OF USE | THE UNIVERSITY OF CHICAGO (US) | 2010-01-21 | — | — | US | disclosed |
| US-7585844-B2 | Comprising nonapeptide wherein first three amino acids and last three amino acids of sequence comprise basic amino acids, and wherein inhibitor comprises at least one D-amino acid or at least one non-hydrolyzable bond; may be used to treat intestinal diseases; infectious, ischemic, inflammatory disease | THE UNIVERSITY OF CHICAGO (US) | 2009-09-08 | — | — | US | disclosed |
| US-20050261196-A1 | Myosin light chain kinase inhibitors and methods of use | THE UNIVERSITY OF CHICAGO (US) | 2005-11-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050261196-A1 | Myosin light chain kinase inhibitors and methods of use | MYLK, MYLK2, MYLK3 | ITGB3 1566/4885ITGA2B 1470/4885SLC7A5 4357/4885 |
| US-20100016242-A1 | MYOSIN LIGHT CHAIN KINASE INHIBITORS AND METHODS OF USE | MYLK, MYLK2, MYLK3 | ITGB3 1566/4885ITGA2B 1470/4885SLC7A5 4357/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.