Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR5 | P51681 | 17/20 | 0.51 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.43 |
| ▸ | DCUN1D1 | Q96GG9 | 1/20 | 0.39 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.37 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4586727 | 0.92 | CCR5 (0.51) | CCR5KCNH2DCUN1D1CACNA1B | |
| SCHEMBL4586809 | 0.89 | CCR5 (0.50) | CCR5KCNH2DCUN1D1CACNA1B | |
| SCHEMBL4586226 | 0.87 | CCR5 (0.50) | CCR5KCNH2DCUN1D1 | |
| SCHEMBL4586221 | 0.86 | CCR5 (0.48) | CCR5KCNH2DCUN1D1CACNA1B | |
| SCHEMBL4244536 | 0.85 | CCR5 (0.69) | CCR5 | |
| SCHEMBL4585956 | 0.85 | CCR5 (0.49) | CCR5KCNH2CACNA1B | |
| SCHEMBL4586351 | 0.83 | CCR5 (0.51) | CCR5KCNH2CACNA1B | |
| SCHEMBL4585482 | 0.83 | CCR5 (0.51) | CCR5KCNH2DCUN1D1 | |
| SCHEMBL4587438 | 0.81 | CCR5 (0.50) | CCR5KCNH2DCUN1D1CACNA1B | |
| SCHEMBL4586733 | 0.80 | CCR5 (0.49) | CCR5KCNH2CACNA1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1708703-A4 | CHEMOKINE RECEPTOR BINDING COMPOUNDS | ANORMED INC (CA) | 2008-04-09 | — | — | EP | claimed |
| EP-1708703-A2 | CHEMOKINE RECEPTOR BINDING COMPOUNDS | ANORMED INC. (CA) | 2006-10-11 | — | — | EP | claimed |
| WO-2005059107-A2 | CHEMOKINE RECEPTOR BINDING COMPOUNDS | ANORMED INC. (CA) | 2005-06-30 | — | — | WO | claimed |
| EP-1708703-A4 | CHEMOKINE RECEPTOR BINDING COMPOUNDS | ANORMED INC (CA) | 2008-04-09 | — | — | EP | disclosed |
| EP-1708703-A2 | CHEMOKINE RECEPTOR BINDING COMPOUNDS | ANORMED INC. (CA) | 2006-10-11 | — | — | EP | disclosed |
| WO-2005059107-A2 | CHEMOKINE RECEPTOR BINDING COMPOUNDS | ANORMED INC. (CA) | 2005-06-30 | — | — | WO | disclosed |