Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KIF11 | P52732 | 1/20 | 0.39 |
| ▸ | GSR | P00390 | 1/20 | 0.38 |
| ▸ | ANPEP | P15144 | 1/20 | 0.37 |
| ▸ | ENPEP | Q07075 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | MMP2 | P08253 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.35 |
| ▸ | GRM3 | Q14832 | 1/20 | 0.35 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.34 |
| ▸ | SLC7A11 | Q9UPY5 | 1/20 | 0.34 |
| ▸ | GABBR2 | O75899 | 1/20 | 0.34 |
| ▸ | GABBR1 | Q9UBS5 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7865836 | 0.80 | SLC7A5 (0.49) | PKMMMP2PTGS1 | |
| SCHEMBL9717076 | 0.79 | KIF11 (0.58) | KIF11ANPEPENPEPNPSR1CYP1A2 | |
| SCHEMBL38107 | 0.77 | NPSR1 (0.43) | GSRNPSR1CYP1A2CYP2D6PKM | |
| SCHEMBL286963 | 0.76 | GSR (0.43) | GSRCYP2D6MAPT | |
| SCHEMBL22323630 | 0.76 | GSR (0.43) | GSRCYP2D6 | |
| SCHEMBL10336616 | 0.76 | KIF11 (0.43) | KIF11ANPEPENPEPNPSR1CYP1A2 | |
| SCHEMBL7944346 | 0.76 | HCAR2 (0.47) | KIF11ANPEPENPEPNPSR1CYP1A2 | |
| SCHEMBL9276515 | 0.76 | GSR (0.41) | GSRNPSR1CYP1A2CYP2D6PKM | |
| SCHEMBL5932816 | 0.75 | GSR (0.42) | GSRCYP2D6MAPT | |
| SCHEMBL9540562 | 0.75 | KDM4E (0.59) | SMN1; SMN2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1797177-A4 | ADDING PHOTOREGULATED AMINO ACIDS TO THE GENETIC CODE | SCRIPPS RESEARCH INST (US) | 2008-07-09 | — | — | EP | claimed |
| EP-1797177-A2 | ADDING PHOTOREGULATED AMINO ACIDS TO THE GENETIC CODE | The Scripps Research Institute (US) | 2007-06-20 | — | — | EP | claimed |
| WO-2006034410-A2 | ADDING PHOTOREGULATED AMINO ACIDS TO THE GENETIC CODE | THE SCRIPPS RESARCH INSTITUTE (US) | 2006-03-30 | — | — | WO | claimed |
| WO-2021072167-A1 | COMPOSITIONS AND METHODS FOR IN VIVO SYNTHESIS OF UNNATURAL POLYPEPTIDES | THE SCRIPPS RESEARCH INSTITUTE (US) | 2021-04-15 | — | — | WO | disclosed |
| EP-1797177-A4 | ADDING PHOTOREGULATED AMINO ACIDS TO THE GENETIC CODE | SCRIPPS RESEARCH INST (US) | 2008-07-09 | — | — | EP | disclosed |
| EP-1797177-A2 | ADDING PHOTOREGULATED AMINO ACIDS TO THE GENETIC CODE | The Scripps Research Institute (US) | 2007-06-20 | — | — | EP | disclosed |
| WO-2006034410-A2 | ADDING PHOTOREGULATED AMINO ACIDS TO THE GENETIC CODE | THE SCRIPPS RESARCH INSTITUTE (US) | 2006-03-30 | — | — | WO | disclosed |