Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APP | P05067 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | PRSS1 | P07477 | 7/20 | 0.37 |
| ▸ | MAOA | P21397 | 1/20 | 0.37 |
| ▸ | MAOB | P27338 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | F2 | P00734 | 2/20 | 0.36 |
| ▸ | PRSS2 | P07478 | 2/20 | 0.36 |
| ▸ | PRSS3 | P35030 | 2/20 | 0.36 |
| ▸ | TMPRSS6 | Q8IU80 | 2/20 | 0.36 |
| ▸ | ST14 | Q9Y5Y6 | 2/20 | 0.36 |
| ▸ | CA12 | O43570 | 1/20 | 0.36 |
| ▸ | CA1 | P00915 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 1/20 | 0.36 |
| ▸ | CA9 | Q16790 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5155265 | 0.88 | APP (0.44) | APPMAPTRAB9AGAAPRSS1 | |
| SCHEMBL7808737 | 0.83 | ADRA2B (0.38) | APPMAPTPRSS1MAOAMAOB | |
| SCHEMBL2560112 | 0.82 | APP (0.41) | APPMAPTRAB9AGAAPRSS1 | |
| SCHEMBL14594023 | 0.82 | APP (0.41) | APPMAPTRAB9AGAAPRSS1 | |
| SCHEMBL14594024 | 0.81 | APP (0.46) | APPMAPTRAB9AGAAPRSS1 | |
| SCHEMBL6744253 | 0.81 | ADRA2B (0.41) | APPMAPTGAAPRSS1MAOA | |
| SCHEMBL180817 | 0.79 | APP (0.55) | APPMAPTRAB9AGAAPRSS1 | |
| SCHEMBL14253823 | 0.79 | APP (0.44) | APPMAPTRAB9AGAAMAOA | |
| SCHEMBL1924337 | 0.79 | TDP1 (0.46) | APPMAPTGAAMAOAMAOB | |
| SCHEMBL3151714 | 0.79 | MAPT (0.64) | MAPTRAB9AGAAMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 68 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6579326-B2 | For dyeing hair | L'OREAL S.A. (FR) | 2003-06-17 | — | — | US | claimed |
| US-6537328-B1 | Hair dye | L'OREAL S.A. (FR) | 2003-03-25 | — | — | US | claimed |
| US-20030028975-A9 | COMPOSITIONS FOR DYEING KERATIN FIBERS, CONTAINING CATIONIC INDOLIZINE DERIVATIVES, AND DYEING PROCESS | L'OREAL S.A. (FR) | 2003-02-13 | — | — | US | claimed |
| US-20010044974-A1 | Compositions for dyeing keratin fibers, containing cationic indolizine derivatives, and dyeing process | BRETON PHILIPPE (FR) | 2001-11-29 | — | — | US | claimed |
| US-5938792-A | APPLYING TO KERATINOUS FIBERS UNDER BASIC CONDITIONS COMPOSITION COMPRISING AMINOINDOLE COUPLER, OXIDATION DYE PRECURSOR, OXIDIZING AGENT | L'OREAL (FR) | 1999-08-17 | — | — | US | claimed |
| US-5752982-A | DYEING HAIR IN LIGHTFAST, WASHFAST COLORS | L'OREAL (FR) | 1998-05-19 | — | — | US | claimed |
| EP-0589952-B1 | USE OF SUPLHUR METAAMINOPHENOLS FOR DYEING KERATINIC FIBRES, TINCTORIAL COMPOSITIONS AND NOVEL COMPOUNDS | OREAL (FR) | 1997-08-27 | — | — | EP | claimed |
| EP-0591373-B1 | META-AMINOPHENOLS, THEIR USE AS COUPLERS FOR OXIDATION DYEING OF KERATINOUS FIBRES, DYE COMPOSITIONS AND METHOD | OREAL (FR) | 1996-05-22 | — | — | EP | claimed |
| EP-0578735-B1 | NOVEL KERATIN FIBRE DYEING METHOD USING AMINOINDOLES, WITH ACID pH, COMPOSITIONS THEREFOR AND NOVEL AMINOINDOLE COMPOUNDS | OREAL (FR) | 1996-01-03 | — | — | EP | claimed |
| US-5478359-A | Applying a hair dyes | L'OREAL (FR) | 1995-12-26 | — | — | US | claimed |
| EP-0506549-B1 | Dyeing composition for keratinous fibers containing oxidation dye precursors and hydroxybenzofurans as couplers and dyeing process making use of such a composition | OREAL (FR) | 1995-10-18 | — | — | EP | claimed |
| US-5443596-A | Keratinous fiber dyeing compositions and processes utilizing oxidation dye precursors in combination with dimethoxy meta-aminophenol couplers | L'OREAL (FR) | 1995-08-22 | — | — | US | claimed |
| EP-0580713-B1 | METHOD FOR DYEING KERATIN FIBRES WITH AMINOINDOLES HAVING ALKALINE pH, AND COMPOSITIONS THEREFOR | OREAL (FR) | 1995-03-01 | — | — | EP | claimed |
| EP-0589952-A1 | USE OF SUPLHUROUS METAAMINOPHENOLS FOR DYING KERATINIC FIBRES, TINCTORIAL COMPOSITIONS AND NOVEL COMPOUNDS. | OREAL (FR) | 1994-04-06 | — | — | EP | claimed |
| US-5203875-A | Hair dyes also using ortho- and para-phenylenediamines or aminophenols; colorfastness; washfastness; perspiration resistance | L'OREAL (FR) | 1993-04-20 | — | — | US | claimed |
| WO-1992022525-A1 | USE OF SUPLHUROUS METAAMINOPHENOLS FOR DYING KERATINIC FIBRES, TINCTORIAL COMPOSITIONS AND NOVEL COMPOUNDS | L'OREAL (FR) | 1992-12-23 | — | — | WO | claimed |
| WO-2026102602-A1 | COMPOSITION FOR DYEING KERATIN FIBERS | L'OREAL (FR) | 2026-05-21 | — | — | WO | disclosed |
| WO-2026102601-A1 | COMPOSITION FOR DYEING KERATIN FIBERS | L'OREAL (FR) | 2026-05-21 | — | — | WO | disclosed |
| US-5203875-A | Hair dyes also using ortho- and para-phenylenediamines or aminophenols; colorfastness; washfastness; perspiration resistance | L'OREAL (FR) | 1993-04-20 | — | — | US | disclosed |
| CN-1063409-A | Indole derivatives is done the application of colour former in the dyeing keratinous fibres process | OREAL (FR) | 1992-08-12 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20010044974-A1 | Compositions for dyeing keratin fibers, containing cationic indolizine derivatives, and dyeing process | KRT18, INMT, KMO | APP 2054/4885MAPT 460/4885RAB9A 4104/4885 |
| US-20030028975-A9 | COMPOSITIONS FOR DYEING KERATIN FIBERS, CONTAINING CATIONIC INDOLIZINE DERIVATIVES, AND DYEING PROCESS | KRT18, INMT, KMO | APP 2143/4885MAPT 530/4885RAB9A 4118/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.