Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.40 |
| ▸ | GFER | P55789 | 1/20 | 0.40 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.40 |
| ▸ | IKBKB | O14920 | 1/20 | 0.37 |
| ▸ | MAP3K14 | Q99558 | 1/20 | 0.37 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.37 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.36 |
| ▸ | ALPL | P05186 | 2/20 | 0.35 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.35 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | RAB9A | P51151 | 2/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.34 |
| ▸ | NOTUM | Q6P988 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | DCUN1D1 | Q96GG9 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL456840 | 0.77 | IKBKB (0.43) | LMNATDP1GFERAPOBEC3GIKBKB | |
| SCHEMBL4637026 | 0.73 | NR1H2 (0.40) | NR1H2ALPLSMN1; SMN2RAB9ANPC1 | |
| SCHEMBL17055629 | 0.62 | IKBKB (0.47) | LMNATDP1GFERAPOBEC3GIKBKB | |
| SCHEMBL20075139 | 0.61 | IKBKB (0.50) | LMNATDP1GFERAPOBEC3GIKBKB | |
| SCHEMBL1143346 | 0.61 | DRD2 (0.46) | LMNATDP1GFERAPOBEC3GIKBKB | |
| SCHEMBL3627117 | 0.61 | L3MBTL1 (0.35) | NR1H2ALPLSMN1; SMN2RAB9ANPC1 | |
| SCHEMBL2766578 | 0.61 | MEN1 (0.40) | LMNANR1H2ALPLSMN1; SMN2RAB9A | |
| SCHEMBL509857 | 0.61 | AHR (0.45) | LMNATDP1SMN1; SMN2RAB9ANPC1 | |
| SCHEMBL676804 | 0.60 | MAOB (0.52) | LMNATDP1SMN1; SMN2NPC1POLB | |
| SCHEMBL8990607 | 0.59 | MAOB (0.57) | LMNASMN1; SMN2NPC1POLBALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2614053-A1 | METHOD FOR PRODUCING PYRIDAZINONE COMPOUNDS AND INTERMEDIATE THEREOF | SUMITOMO CHEMICAL COMPANY LIMITED (JP) | 2013-07-17 | — | — | EP | disclosed |
| WO-2012033225-A1 | METHOD FOR PRODUCING PYRIDAZINONE COMPOUNDS AND INTERMEDIATE THEREOF | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2012-03-15 | — | — | WO | disclosed |