Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.62 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.62 |
| ▸ | HPGDS | O60760 | 1/20 | 0.55 |
| ▸ | ATM | Q13315 | 1/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.52 |
| ▸ | HTR4 | Q13639 | 2/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | MCHR1 | Q99705 | 6/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.47 |
| ▸ | SMYD3 | Q9H7B4 | 3/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | CNR1 | P21554 | 1/20 | 0.45 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.45 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4590660 | 0.86 | MEN1 (0.62) | MEN1KMT2AHPGDSATML3MBTL1 | |
| SCHEMBL2957973 | 0.86 | MEN1 (0.62) | MEN1KMT2AHPGDSATML3MBTL1 | |
| Hydrochloric Acid SCHEMBL2954893 | 0.85 | MEN1 (0.60) | MEN1KMT2AHPGDSATML3MBTL1 | |
| SCHEMBL2953714 | 0.83 | MEN1 (0.58) | MEN1KMT2AHPGDSATML3MBTL1 | |
| SCHEMBL29530916 | 0.81 | ALDH1A1 (0.63) | MEN1KMT2AHPGDSALDH1A1HTR4 | |
| SCHEMBL1711687 | 0.81 | ALDH1A1 (0.63) | MEN1KMT2AHPGDSALDH1A1HTR4 | |
| SCHEMBL2470064 | 0.81 | MEN1 (0.84) | MEN1KMT2AATML3MBTL1ALDH1A1 | |
| SCHEMBL2963930 | 0.80 | MEN1 (0.57) | MEN1KMT2AHPGDSATML3MBTL1 | |
| SCHEMBL18396293 | 0.80 | HPGDS (0.62) | MEN1KMT2AHPGDSHTR4SMYD3 | |
| Hydrochloric Acid SCHEMBL31722313 | 0.80 | ALDH1A1 (0.62) | MEN1KMT2AHPGDSALDH1A1HTR4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1893603-A1 | PIPERIDIN-4-YL-AMIDE DERIVATIVES AND THEIR USE AS SST RECEPTOR SUBTYPE 5 ANTAGONISTS | F. Hoffmann-La Roche AG (CH) | 2008-03-05 | — | — | EP | disclosed |
| WO-2006128803-A1 | PIPERIDIN-4-YL-AMIDE DERIVATIVES AND THEIR USE AS SST RECEPTOR SUBTYPE 5 ANTAGONISTS | F. HOFFMANN-LA ROCHE AG (CH) | 2006-12-07 | — | — | WO | disclosed |