Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGLN3 | Q9H6Z9 | 1/20 | 0.44 |
| ▸ | TBXAS1 | P24557 | 11/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | TLR2 | O60603 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL47371 | 0.86 | EGLN3 (0.50) | EGLN3TBXAS1ALDH1A1MEN1KMT2A | |
| SCHEMBL14331530 | 0.84 | TLR2 (0.40) | EGLN3TBXAS1ALDH1A1TSHRTLR2 | |
| SCHEMBL24403618 | 0.84 | EGLN3 (0.37) | EGLN3TBXAS1ALDH1A1TLR2 | |
| SCHEMBL14331556 | 0.83 | TLR2 (0.41) | EGLN3TBXAS1ALDH1A1TSHRTLR2 | |
| SCHEMBL774881 | 0.83 | RAB9A (0.53) | RAB9AMEN1KMT2ATSHR | |
| SCHEMBL14331565 | 0.82 | TLR2 (0.40) | EGLN3TBXAS1ALDH1A1TSHRTLR2 | |
| SCHEMBL21164179 | 0.82 | TLR2 (0.38) | EGLN3TBXAS1ALDH1A1TLR2 | |
| SCHEMBL15223333 | 0.82 | TLR2 (0.38) | EGLN3TBXAS1ALDH1A1TLR2 | |
| SCHEMBL14331531 | 0.81 | TLR2 (0.43) | EGLN3TBXAS1ALDH1A1TLR2 | |
| SCHEMBL5707877 | 0.80 | EGLN3 (0.53) | EGLN3TBXAS1ALDH1A1TLR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2723301-B1 | POLYMERIZABLE ANTIBACTERIAL/ANTIMICROBIAL RESINS AND USE IN DENTAL COMPOSITIONS | DENTSPLY SIRONA INC (US) | 2020-03-04 | — | — | EP | disclosed |
| US-RE47512-E1 | Imidazole and imidazolium resins and methods for preparing curable imidazolium antimicrobial resins | DENTSPLY SIRONA INC. (US) | 2019-07-16 | — | — | US | disclosed |
| US-20170143594-A1 | ORTHODONTIC CEMENT COMPOSITIONS AND METHODS OF USE THEREOF | DENTSPLY SIRONA INC (US) | 2017-05-25 | — | — | US | disclosed |
| US-20170143594-A1 | ORTHODONTIC CEMENT COMPOSITIONS AND METHODS OF USE THEREOF | DENTSPLY SIRONA INC (US) | 2017-05-25 | — | — | US | disclosed |
| EP-2571908-B1 | POLYMERIZABLE IONIC LIQUID COMPOSITIONS | 3M INNOVATIVE PROPERTIES CO (US) | 2017-04-26 | — | — | EP | disclosed |
| US-8779024-B2 | Acid-neutralizing resins and hardenable dental compositions thereof | DENTSPLY INTERNATIONAL INC. (US) | 2014-07-15 | — | — | US | disclosed |
| US-8747831-B2 | Method and antibacterial/antimicrobial compositions in dental compositions | DENTSPLY INTERNATIONAL INC. (US) | 2014-06-10 | — | — | US | disclosed |
| US-20130225716-A1 | Acid-neutralizing Resins and Hardenable Dental Compositions Thereof | DENTSPLY INTERNATIONAL INC. (US) | 2013-08-29 | — | — | US | disclosed |
| US-8383721-B2 | Polymerizable ionic liquid compositions | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2013-02-26 | — | — | US | disclosed |
| US-8383721-B2 | Polymerizable ionic liquid compositions | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2013-02-26 | — | — | US | disclosed |
| US-20120328553-A1 | METHOD AND ANTIBACTERIAL/ANTIMICROBIAL COMPOSITIONS IN DENTAL COMPOSITIONS | DENTSPLY INTERNATIONAL INC. (US) | 2012-12-27 | — | — | US | disclosed |
| WO-2011146326-A1 | POLYMERIZABLE IONIC LIQUID COMPOSITIONS | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2011-11-24 | — | — | WO | disclosed |
| US-20110288227-A1 | POLYMERIZABLE IONIC LIQUID COMPOSITIONS | 3M INNOVATIVE PROPERTIES COMPANY | 2011-11-24 | — | — | US | disclosed |
| US-20110288227-A1 | POLYMERIZABLE IONIC LIQUID COMPOSITIONS | 3M INNOVATIVE PROPERTIES COMPANY | 2011-11-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170143594-A1 | ORTHODONTIC CEMENT COMPOSITIONS AND METHODS OF USE THEREOF | PCNA, DOCK5, BMI1 | EGLN3 3539/4885TBXAS1 4780/4885ALDH1A1 4564/4885 |
| US-20130225716-A1 | Acid-neutralizing Resins and Hardenable Dental Compositions Thereof | ASIC1, ASIC3, ARCN1 | EGLN3 1028/4885TBXAS1 2186/4885ALDH1A1 2473/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.