Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 4/20 | 0.43 |
| ▸ | RIPK1 | Q13546 | 3/20 | 0.38 |
| ▸ | XIAP | P98170 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31305862 | 0.83 | SIGMAR1 (0.49) | SIGMAR1XIAP | |
| SCHEMBL4574098 | 0.78 | RIPK1 (0.38) | RIPK1 | |
| SCHEMBL4575085 | 0.78 | RIPK1 (0.38) | RIPK1 | |
| SCHEMBL14566377 | 0.77 | SIGMAR1 (0.51) | SIGMAR1XIAP | |
| SCHEMBL2022959 | 0.76 | XIAP (0.40) | XIAP | |
| SCHEMBL31305848 | 0.76 | SIGMAR1 (0.42) | SIGMAR1XIAP | |
| SCHEMBL4678046 | 0.74 | SIGMAR1 (0.56) | SIGMAR1 | |
| SCHEMBL4590115 | 0.74 | SIGMAR1 (0.40) | SIGMAR1RIPK1 | |
| SCHEMBL5058871 | 0.74 | SIGMAR1 (0.56) | SIGMAR1 | |
| SCHEMBL3165725 | 0.74 | SIGMAR1 (0.56) | SIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008134035-A1 | ALPHA-UNSUBSTITUTED ARYLMETHYL PIPERAZINE PYRAZOLO[1,5-A] PYRIMIDINE AMIDE DERIVATIVES | PANACOS PHARMACEUTICALS, INC. (US) | 2008-11-06 | — | — | WO | disclosed |
| WO-2008134035-A1 | ALPHA-UNSUBSTITUTED ARYLMETHYL PIPERAZINE PYRAZOLO[1,5-A] PYRIMIDINE AMIDE DERIVATIVES | PANACOS PHARMACEUTICALS, INC. (US) | 2008-11-06 | — | — | WO | disclosed |