Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.59 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.59 |
| ▸ | TAS1R2 | Q8TE23 | 1/20 | 0.59 |
| ▸ | SMYD3 | Q9H7B4 | 7/20 | 0.56 |
| ▸ | PKM | P14618 | 1/20 | 0.55 |
| ▸ | NPC1 | O15118 | 1/20 | 0.54 |
| ▸ | HPGD | P15428 | 1/20 | 0.52 |
| ▸ | RAB9A | P51151 | 1/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.52 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.51 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.49 |
| ▸ | CCR2 | P41597 | 1/20 | 0.49 |
| ▸ | PRSS1 | P07477 | 2/20 | 0.49 |
| ▸ | PRSS2 | P07478 | 2/20 | 0.49 |
| ▸ | PRSS3 | P35030 | 2/20 | 0.49 |
| ▸ | ST14 | Q9Y5Y6 | 2/20 | 0.49 |
| ▸ | F2 | P00734 | 1/20 | 0.48 |
| ▸ | GRM5 | P41594 | 2/20 | 0.48 |
| ▸ | KDM1A | O60341 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2472926 | 0.89 | TAS1R3 (0.67) | TAS1R3TAS1R1TAS1R2SMYD3PKM | |
| SCHEMBL4609353 | 0.84 | TAS1R3 (0.62) | TAS1R3TAS1R1TAS1R2PKMNPC1 | |
| SCHEMBL4575139 | 0.81 | TAS1R3 (0.61) | TAS1R3TAS1R1TAS1R2PKMNPC1 | |
| SCHEMBL6455818 | 0.80 | SMYD3 (0.58) | SMYD3MCHR1EPHX2PRSS1PRSS2 | |
| SCHEMBL6455822 | 0.80 | SMYD3 (0.58) | SMYD3MCHR1EPHX2PRSS1PRSS2 | |
| SCHEMBL6455626 | 0.79 | SMYD3 (0.69) | SMYD3PKMNPC1HPGDRAB9A | |
| SCHEMBL6455623 | 0.79 | SMYD3 (0.69) | SMYD3PKMNPC1HPGDRAB9A | |
| SCHEMBL1580017 | 0.77 | TAS1R3 (0.58) | TAS1R3TAS1R1TAS1R2PKMNPC1 | |
| SCHEMBL10294731 | 0.76 | NPC1 (0.66) | TAS1R3TAS1R1TAS1R2SMYD3PKM | |
| SCHEMBL4574282 | 0.75 | USP30 (0.60) | TAS1R3TAS1R1TAS1R2PKMHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008065500-A2 | HETEROARYL AMIDES AS TYPE I GLYCINE TRANSPORT INHIBITORS | PFIZER PRODUCTS INC. (US) | 2008-06-05 | — | — | WO | disclosed |