Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.62 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.62 |
| ▸ | TAS1R2 | Q8TE23 | 1/20 | 0.62 |
| ▸ | PKM | P14618 | 1/20 | 0.52 |
| ▸ | RAB9A | P51151 | 5/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.52 |
| ▸ | HPGD | P15428 | 1/20 | 0.52 |
| ▸ | NPC1 | O15118 | 5/20 | 0.51 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.49 |
| ▸ | HPGDS | O60760 | 1/20 | 0.49 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.49 |
| ▸ | GRM5 | P41594 | 3/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | GFER | P55789 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2472926 | 0.86 | TAS1R3 (0.67) | TAS1R3TAS1R1TAS1R2PKMRAB9A | |
| SCHEMBL4590917 | 0.84 | TAS1R3 (0.59) | TAS1R3TAS1R1TAS1R2PKMRAB9A | |
| SCHEMBL10294731 | 0.81 | NPC1 (0.66) | TAS1R3TAS1R1TAS1R2PKMRAB9A | |
| SCHEMBL4574282 | 0.79 | USP30 (0.60) | TAS1R3TAS1R1TAS1R2PKMRAB9A | |
| SCHEMBL4575139 | 0.78 | TAS1R3 (0.61) | TAS1R3TAS1R1TAS1R2PKMRAB9A | |
| SCHEMBL5751349 | 0.77 | TAS1R3 (1.00) | TAS1R3TAS1R1TAS1R2 | |
| SCHEMBL4590508 | 0.76 | CARM1 (0.57) | MCHR1ALDH1A1TSHR | |
| SCHEMBL1580017 | 0.74 | TAS1R3 (0.58) | TAS1R3TAS1R1TAS1R2PKMRAB9A | |
| SCHEMBL16219478 | 0.74 | TAS1R3 (0.53) | TAS1R3TAS1R1TAS1R2PKMRAB9A | |
| SCHEMBL3678482 | 0.73 | MCHR1 (0.60) | RAB9ASMN1; SMN2NPC1EPHX2HPGDS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008065500-A2 | HETEROARYL AMIDES AS TYPE I GLYCINE TRANSPORT INHIBITORS | PFIZER PRODUCTS INC. (US) | 2008-06-05 | — | — | WO | disclosed |