Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAS2R14 | Q9NYV8 | 1/20 | 0.45 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | NPC1 | O15118 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | PKM | P14618 | 1/20 | 0.37 |
| ▸ | NNMT | P40261 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | ERN1 | O75460 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL641895 | 0.85 | TAS2R14 (0.37) | TAS2R14TRPM8KMT2AMAPK1SMN1; SMN2 | |
| SCHEMBL4591092 | 0.80 | CYP1A2 (0.45) | TRPM8KMT2ATSHRHTTSMN1; SMN2 | |
| SCHEMBL28661271 | 0.79 | KCNH2 (0.41) | TRPM8KMT2ATSHRHTTSMN1; SMN2 | |
| SCHEMBL4588961 | 0.77 | TRPM8 (0.42) | TRPM8TSHRHTTSMN1; SMN2ALDH1A1 | |
| SCHEMBL207440 | 0.76 | KDM4E (0.59) | KMT2ATSHRSMN1; SMN2ALDH1A1KDM4E | |
| SCHEMBL29501241 | 0.76 | KDM4E (0.59) | KMT2ATSHRSMN1; SMN2ALDH1A1KDM4E | |
| SCHEMBL1885189 | 0.74 | TAS2R14 (0.39) | TAS2R14KMT2ASMN1; SMN2KDM4EMEN1 | |
| SCHEMBL12252457 | 0.73 | KDM4E (0.44) | KMT2AALDH1A1KDM4EMEN1NNMT | |
| SCHEMBL12640354 | 0.70 | ALDH1A1 (0.42) | KMT2AALDH1A1MEN1NPC1LMNA | |
| SCHEMBL1890222 | 0.70 | TAS2R14 (0.36) | TAS2R14ERN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008063888-A2 | COMPOUNDS MODULATING C-FMS AND/OR C-KIT ACTIVITY AND USES THEREFOR | PLEXXIKON, INC. (US) | 2008-05-29 | — | — | WO | disclosed |