Ammonia Solution, Strong

Ammonia Solution, Strong

SCHEMBL4591099

CCCc1ccc2cc1-2.N

nearest known ligand 0.46

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Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALOX5 P09917 2/20 0.46
BRD4 O60885 1/20 0.43
GABRA1 P14867 4/20 0.39
GABRB2 P47870 4/20 0.39
GABRA5 P31644 1/20 0.36
GABRA3 P34903 1/20 0.36
GABRA2 P47869 1/20 0.36
CNR1 P21554 1/20 0.34
CNR2 P34972 1/20 0.34
RARA P10276 3/20 0.33
RARB P10826 3/20 0.33
RARG P13631 3/20 0.33
PRKCI P41743 1/20 0.33
ESR1 P03372 2/20 0.33
ESR2 Q92731 2/20 0.33
TYR P14679 1/20 0.32
HMGCR P04035 1/20 0.32
PPARA Q07869 1/20 0.32
HSP90AA1 P07900 1/20 0.31
ELANE P08246 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5595171 0.81 SMN1; SMN2 (0.40) ALOX5BRD4RARARARBRARG
Ammonia Solution, Strong SCHEMBL4590632 0.80
SCHEMBL8336193 0.74 BRD4 (0.37) ALOX5BRD4GABRA1GABRB2PPARA
SCHEMBL28517648 0.73 HSD17B1 (0.46) ALOX5ESR1ESR2TYR
SCHEMBL19121996 0.73 HRH3 (0.50)
SCHEMBL9876309 0.72 CTSS (0.44) ALOX5BRD4TYRPPARAELANE
SCHEMBL23277216 0.70 ESR2 (0.50) ALOX5ESR1ESR2TYR
SCHEMBL27398014 0.70 PTGDR2 (0.43)
SCHEMBL11323213 0.70 PSMB5 (0.42) RARARARBRARGTYRPPARA
SCHEMBL28668871 0.70 TRPA1 (0.37) ALOX5BRD4GABRA1GABRB2GABRA5

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20080244963-A1 Lead-Free Aviation Fuel TOTAL FRANCE (FR) 2008-10-09 US claimed
US-20080244963-A1 Lead-Free Aviation Fuel TOTAL FRANCE (FR) 2008-10-09 US disclosed
EP-1971668-A1 LEAD-FREE AVIATION FUEL Total France (FR) 2008-09-24 EP disclosed
WO-2007074226-A1 LEAD-FREE AVIATION FUEL TOTAL FRANCE (FR) 2007-07-05 WO disclosed