SCHEMBL459120

SCHEMBL459120

O=C(O)CCCCCNc1ccc([N+](=O)[O-])c2nonc12

nearest known ligand 0.76

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GSTM2 P28161 1/20 0.76
HRH3 Q9Y5N1 2/20 0.63
MEN1 O00255 6/20 0.58
KMT2A Q03164 6/20 0.58
USP2 O75604 1/20 0.58
HTT P42858 1/20 0.58
RECQL P46063 1/20 0.58
THRB P10828 1/20 0.54
HPGD P15428 1/20 0.54
L3MBTL1 Q9Y468 1/20 0.54
MYC P01106 4/20 0.53
MAX P61244 1/20 0.53
SUCNR1 Q9BXA5 1/20 0.53
IDO1 P14902 1/20 0.52
MIF P14174 1/20 0.52
S1PR4 O95977 1/20 0.52
S1PR1 P21453 1/20 0.52
S1PR3 Q99500 1/20 0.52
S1PR5 Q9H228 1/20 0.52
MAPT P10636 1/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15515612 1.00 GSTM2 (0.76) GSTM2HRH3MEN1KMT2AUSP2
SCHEMBL31320442 1.00 GSTM2 (0.76) GSTM2HRH3MEN1KMT2AUSP2
SCHEMBL285019 1.00 GSTM2 (0.76) GSTM2HRH3MEN1KMT2AUSP2
SCHEMBL15516469 1.00 GSTM2 (0.76) GSTM2HRH3MEN1KMT2AUSP2
SCHEMBL592618 1.00 GSTM2 (0.76) GSTM2HRH3MEN1KMT2AUSP2
SCHEMBL14617994 0.95 GSTM2 (0.72) GSTM2HRH3MEN1KMT2AUSP2
SCHEMBL30892505 0.91 GSTM2 (0.76) GSTM2HRH3MEN1KMT2AUSP2
SCHEMBL30892506 0.91 GSTM2 (0.76) GSTM2HRH3MEN1KMT2AUSP2
SCHEMBL17525024 0.90 GSTM2 (0.67) GSTM2HRH3MEN1KMT2AUSP2
SCHEMBL13524165 0.89 GSTM2 (0.74) GSTM2HRH3MEN1KMT2AUSP2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 615 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260124148-A1 POLYPEPTIDE FORMULATIONS FOR ORAL DELIVERY BHAMIS RES LABORATORY PVT LTD (IN) 2026-05-07 US claimed
EP-4601623-A1 POLYPEPTIDE FORMULATIONS FOR ORAL DELIVERY Bhami's Research Laboratory, Pvt. Ltd. (IN) 2025-08-20 EP claimed
CN-113454099-B Detection of colonography in vivo using near infrared peptides targeting over-expression of cMET 密歇根大学董事会 2025-05-27 CN claimed
EP-3497452-B1 DIAGNOSIS, PREVENTION, AND/OR TREATMENT OF AUTOIMMUNE DISEASES IMMUNOWORK LLC (US) 2025-03-05 EP claimed
EP-3624846-B1 HIGH CONCENTRATION PROTEIN FORMULATIONS WITH REDUCED VISCOSITY INCLUDING A COMBINATION OF NICOTINIC ACID AND TRYOPTOPHAN BHAMIS RES LABORATORY PVT LTD (IN) 2024-08-07 EP claimed
WO-2024079738-A1 ORAL POLYPEPTIDE FORMULATIONS Bhami's Research Laboratory, Pvt. Ltd. (IN) 2024-04-18 WO claimed
WO-2024079739-A1 POLYPEPTIDE FORMULATIONS FOR ORAL DELIVERY Bhami's Research Laboratory, Pvt. Ltd. (IN) 2024-04-18 WO claimed
US-20240115702-A1 HIGH CONCENTRATION PROTEIN FORMULATIONS WITH REDUCED VISCOSITY Bhami's Research Laboratory, Pvt. Ltd. (IN) 2024-04-11 US claimed
EP-4323007-A1 POLYPEPTIDE FORMULATIONS Bhami's Research Laboratory, Pvt. Ltd. (IN) 2024-02-21 EP claimed
CN-117460536-A Polypeptide formulations 巴米研究实验室私人有限公司 2024-01-26 CN claimed
EP-1807103-A2 MODULATORS OF RETINOL-RETINOL BINDING PROTEIN (RBP)-TRANSTHYRETIN (TTR) COMPLEX FORMATION Sirion Therapeutics, Inc. (US) 2007-07-18 EP claimed
US-20070098684-A9 Methods of reducing aggregation of IL-1ra RAIBEKAS ANDREI 2007-05-03 US claimed
US-20070099235-A1 Method for designing surfaces BIO-LAYER PTY LIMITED (AU) 2007-05-03 US claimed
EP-1700244-A1 A METHOD FOR DESIGNING SURFACES Bio-Layer Pty Limited (AU) 2006-09-13 EP claimed
WO-2006052860-A2 MODULATORS OF RETINOL-RETINOL BINDING PROTEIN (RBP)-TRANSTHYRETIN (TTR) COMPLEX FORMATION SIRION THERAPEUTICS, INC. (US) 2006-05-18 WO claimed
US-20060094063-A1 Modulators of retinol-retinol binding protein (RBP)-transthyretin (TTR) complex formation SYTERA, INC. (US) 2006-05-04 US claimed
US-20050282752-A1 Reducing aggregation of an aggregating interleukin-1 receptor antagonist (IL-1ra); rheumatoid arthritis SWEDISH ORPHAN BIOVITRUM AB (PUBL) (SE) 2005-12-22 US claimed
US-20050271618-A1 Methods of reducing aggregation of IL-1ra SWEDISH ORPHAN BIOVITRUM AB (PUBL) (SE) 2005-12-08 US claimed
WO-2005057462-A1 A METHOD FOR DESIGNING SURFACES BIO-LAYER PTY LIMITED (AU) 2005-06-23 WO claimed
US-20030035755-A1 Organic electroluminescence (OEL)-based biochips HELIX TECHNOLOGY INC. (TW) 2003-02-20 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240115702-A1 HIGH CONCENTRATION PROTEIN FORMULATIONS WITH REDUCED VISCOSITY ALB, TTR, MAX GSTM2 3945/4885HRH3 4685/4885MEN1 1928/4885
US-20050271618-A1 Methods of reducing aggregation of IL-1ra IL1RN, IL1A, IL1B GSTM2 2752/4885HRH3 3393/4885MEN1 4501/4885
US-20070098684-A9 Methods of reducing aggregation of IL-1ra IL1RN, IL1A, IL1B GSTM2 2752/4885HRH3 3393/4885MEN1 4501/4885
US-20260124148-A1 POLYPEPTIDE FORMULATIONS FOR ORAL DELIVERY GLP1R, TTR, IAPP GSTM2 4387/4885HRH3 3285/4885MEN1 1288/4885
US-20060094063-A1 Modulators of retinol-retinol binding protein (RBP)-transthyretin (TTR) complex formation RBP1, TTR, RBP4 GSTM2 3042/4885HRH3 4219/4885MEN1 4500/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.